A nanobody-based anti-inflammatory treatment against Pseudomonas aeruginosa-induced inflammation in chronic lung diseases. Ghent University
Chronic lung inflammation by Pseudomonas aeruginosa is an important driver of pathogenesis in patients with cystic fibrosis (CF), chronic obstructive pulmonary disease, and non-CF bronchiectasis. Therapies directed at the host inflammatory response hold great promise since it is the major process leading to destruction of lung tissue during infection. The objective of this project is to develop an effective therapy against P. ...