Projects
In vitro PBDE's metabolism by pet-animals liver microsomes – evaluation of their potential on assessing human exposure to indoor contaminants. University of Antwerp
Re-balancing cellular fatty acid metabolism to mend the failing heart and damaged brain Hasselt University
Ecophysiological basic equipment for the fundamental analysis of the interaction between water relations and carbon metabolism in plants Ghent University
The ecophysiological basic equipment of the laboratory of Plant ecology consists of (1) CO2 en H2O gas exchange systems to measure photosynthesis, respiration and transpiration, (2) devices to measure chlorophyll fluorescence and (3) plant sensors to measure online sap flow, stem diameter variations (diameter fluctuations/growth), internal CO2- transport and cavitation. This equipment is used to strengthen existing research lines (including ...
Unraveling the influence of diseases on the metabolism of xenobiotics by the gut microbiome. University of Antwerp
Study of fatty acid modification and metabolism on the activity of quorum sensing molecules and lipopeptides produced by Pseudomonas spp. Ghent University
Pseudomonads produce antimicrobial or cytotoxic cyclic lipopeptides (CLPs) and quorum sensing signal molecules, i.e. N-acyl homoserine lactones (AHLs) as interesting secondary metabolites. The overall goal is a) the identification of the role of AHL-mediated quorum sensing mechanisms in regulating secondary metabolite production (CLPs) and b) the elucidtation of fatty acid-based biosynthetic pathways and SAR of CLPs.
Pathway discovery in ferulic acid metabolism with relevance to lignin biosynthesis Ghent University
Ferulic acid is a precursor for several important metabolic classes (including lignin) in plants, but is nevertheless barely studied. This project aims at pathway discovery in the FA metabolism in the model system Arabidopsis via metabolomic and reverse-genetic techniques.