< Back to previous page

Researcher

Debby Van Dam

  • Research interest:Animal modelling of disorders with neurological symptomatologyCognitive and behavioral alterations in Alzheimer’s disease and related neurodegenerative disorders Neurochemical and neuropathological correlates of behavioral alterationsIn-depth phenotyping of rodent models via assessment of various levels of learning and memory , behavioral alterations (e.g. aggression, circadian rhythm changes, anxiety), motor performance, EEG-based sleep or epilepsy studies.Rodent surgery including stereotactic procedures(non)pharmacological interventions with symptomatic or disease-modifying procedures Behavioral and biochemical biomarkers of Alzheimer’s disease in Down syndrome
  • Keywords:TRANSLATIONAL NEUROSCIENCES, BEHAVIOURAL EXPERIMENTS, BRAIN AGEING, NEUROCHEMISTRY, NEURODEGENERATIVE BRAIN DISEASES, ALZHEIMER DEMENTIA, DEMENTIA, Biomedical sciences (incl. biochemistry)
  • Disciplines:Behavioural neuroscience, Cognitive neuroscience, Neurological and neuromuscular diseases, Neurophysiology
  • Research techniques:- Cognitive and behavioural evaluation in rodents- Pharmacological and non-pharmacological modulation of behavioural alterations- In vivo electrophysiology (sleep, epilepsy)- Neurodegenerative disorders, including Alzheimer's disease and related disorders- Animal models of neurodegenerative disorders- Surgical and stereotaxic techniques in rodents- Neurochemical and neuropathological correlaten of behavioural alterations and brain functions - Neurophysiology and behavioural neurosciences - Laboratory animal techniques including project design, legislative framework, animal welfare and ethical considerations
  • Users of research expertise:Researchers requiring in-depth phenotyping and validation of rodent models including neurochemical and neuropathological correlates, pharmacological interventions and surgical procedures