Projects
Link between residual beta cell function and glycemic variability in (pre)type 1 diabetes Vrije Universiteit Brussel
Influence of glycemic variability on autonomic and cardiovascular function, and its modulation by postprandial exercise training in patients with diabetes type 1 Ghent University
Type 1 diabetes is characterized by chronic hyperglycemia and by acute glycemic fluctuations. The role of this glycemic variability (GV) in the development of diabetic complications is subject of debate. In this study we want to evaluate the impact of GV on autonomic function and vascular complications, as well as to investigate the effects of postprandial exercise on these parameters.
Relation between residual beta cell function and glycemic variability in (pre)type 1 diabetes. University of Antwerp
Relation between residual beta cell function and glycemic variability in (pre) type 1 diabetes Ghent University
Type 1 diabetes develops when 60 to 90% of insulin-producing beta cellsahve been destroyed. This cell loss leads to greater variability of
blood glucose levels both before and after diagnosis. This variability is predictive of progression to clinical onset of diabetes in risk groups and of
frequenc of hypoglycemic events in patients. Novel beta cell therapy trials aim to prevent or cure diabetes by trying to preserve or restore ...
The association between new parameters of glycaemic control and arterial stiffness in type 1 diabetes, and its modulation by high-intensity interval exercise. Ghent University
BACKGROUND 1. New parameters of glycaemic control by use of continuous glucose monitoring (CGM; such as time in range, glycaemic variability) are of increasing interest in type 1 diabetes (T1DM) clinical practice. Poor glycaemic control negatively affects arterial stiffness, a valuable predictor for cardiovascular disease. However, reliable data using the state-of-the-art methodology (i.e. CGM) are missing. 2. Easy implementable strategies to ...
Analytical and clinical validation of biomarkers of beta cell damage in type 1 diabetes Vrije Universiteit Brussel
The role of GLucose homeostasis and metabOlomics in pregnancy outcomes afteR barIAtric surgery: the GLORIA study. KU Leuven
Glucose homeostasis, metabolomics and pregnancy outcomes after bariatric surgery: the GLORIA study The prevalence of obesity and metabolic syndrome is increasing at an alarming rate worldwide. Obesity in women is associated with infertility and miscarriages. During pregnancy, obesity is associated with increased risk of gestational diabetes mellitus (GDM), preeclampsia, macrosomia and caesarean delivery. For women with a body mass index (BMI) ...
INTERPLAY WITHIN THE DAY: optimizing intra-day glucose control by intervening on the day-to-day 24-hour movement behavior patterns in adults with type 1 diabetes mellitus. Ghent University
Only 24.9% of the Belgian adults (25-50 years) with type 1 diabetes mellitus (T1DM) achieve the glycemic target. This can be explained by the challenging day-to-day diabetes management which places a substantial burden on this population. However, a tight glucose control is fundamental in order to prevent the development of acute and chronic complications. Despite the added value of continue glucose monitors to glucose control, optimizing ...