Unbiased genomic and epigenomic profiling of cell-free plasma DNA for non-invasive cancer screening KU Leuven
Cancer rates are increasing worldwide. A heavier focus on prevention and early detection is required to complement new and improved treatments. We recently optimized a massive parallel sequencing-based analysis pipeline for non-invasive prenatal testing (NIPT) and identified on cellfree DNA samples of 10000 asymptomatic pregnant women 6 genomic representation (GR) profiles reminiscent of cancer-related copy number profiles. These incidental ...