Projects
Local and systemic immune interactions in malignant gliomas KU Leuven
Glioblastoma (GBM), the most frequent primary intrinsic brain tumor, is without any doubt one of the most devastating diseases known to mankind. GBM are currently being treated with neurosurgical resection followed by radio- and chemotherapy. However, despite this treatment, prognosis for these patients is grim with a median survival of only 15 months and less than 20% 3-year survival rates. Already at diagnosis, GBM cells are infiltrating ...
Functional connectivity of the language network as a non-invasive predictor for language outcome in patients with brain gliomas Ghent University
Functional connectivity analysis is a novel technique that allows studying the neuronal interaction and causal directions of regional brain activation during language processing This technique is promising for clinical purposes as it is applicable in the interpretation of functional activation in patients with brain lesions in language related areas The analysis of an individual connectome may be able to assist in delineating the surgical ...
The role of galectin-1 in macrophage accumulation, phenotype and function in high-grade gliomas. KU Leuven
High-grade gliomas (HGG) are the most common primary tumors in the central nervous system in adults. In spite of multidisciplinary treatment the prognosis remains dismal with a median survival expectancy of 15 months. In search for new treatment strategies, immunotherapy has yielded promising results. However, only a minor subset of HGG patients seems to benefit from active immunotherapy. One of the major factors that limits the efficacy of ...
Development of a novel treatment strategy combining cell therapy with immune priming for paediatric high-grade gliomas. University of Antwerp
Development of a novel treatment strategy combining cell therapy with immune priming for paediatric high-grade gliomas. University of Antwerp
Therapy respons of high-grade gliomas to radiation and chemotherapy using positron emission tomography (PET) with 18F-fluoromethylcholine Ghent University
We aim to investigate the sensitivity/resistence of high-grade gliomas to radiation and chemotherapy (temozolomide) based on cell cultures and an in vivo tumour model in rodents. We herefore use functional imaging, namely positron emission tomography (PET), with 18F-fluoromethylcholine as a tracer. The information is od potential use in case of local tumour recurrence.
‘The rosy gloom of battle overhead’, An artistic research into the atmospheric layers of history KU Leuven
‘The rosy gloom of battle overhead’ An artistic research into the atmospheric layers of history
The purpose of the proposed research is to explore the actions and procedures that are fundamental to my work as a visual artist. This artistic praxis is inspired by the historical method that I learnt as a history student at university, but gradually distinguished itself by creating space for intuition and attention to the image. The ...
Throwing immunity off the scent of the invasion: the role of olfactory ensheating glia in airway infection. University of Antwerp
LivingLab in Carabayllo , Lima - Applied nature-based solutions (NBS) to help recover lomas and urban green in the surroundings of the lomas of Carabayllo KU Leuven
The main goal of this project is to improve (or start the improvement process) the life quality of the Carabayllo residents by raising awareness of the important value that lomas represent and showing them that it is also possible to use the local (lomas) vegetation as a source of urban green in thei own houses, which will help them to make use better the green spaces (urban farming for instance)