Investigation towards the importance for virulence and biofilm formation of a novel pathway for glycerol biosynthesis in the human fungal pathogen Candida albicans KU Leuven
Candida albicans is an opportunistic fungal pathogen that often colonizes the skin and mucosal surfaces of healthy individuals. However, in immunocompromised patients, it can cause diseases leading to blood-stream infections and eventually death. Currently, a major problem in hospitals with this pathogen is its capacity to form biofilms (i.e. three-dimensional structures consisting of yeast and hyphal cells and surrounded by an extracellular ...