Role of virus-derived DNA synthesis in the amplification of insect antiviral signals KU Leuven
The study of antiviral mechanisms stands as important as ever. In insects, the largest and most diverse class of animals, antiviral immunity mainly relies on virus-derived small RNAs (sRNAs), in a process generally known as RNA interference (RNAi). Specifically, virus-derived sRNAs are incorporated into RNA-induced silencing complexes, to find target viral transcripts by Watson-Crick base pairing. At this point, the targeted viral transcripts ...