Researcher
Patrick Pauwels
- Keywords:Medicine
Affiliations
- Center for Oncological Research (CORE) (Research group)
Member
From1 Jan 2019 → Today - Molecular Imaging, Pathology, Radiotherapy & Oncology (MIPRO) (Research group)
Member
From1 Oct 2009 → 31 Dec 2018
Projects
1 - 10 of 23 results
- Combined targeting of the epidermal growth factor receptor and the innate immune system: a novel therapeutic approach for the treatment of head and neck cancer.From1 Jan 2019 → TodayFunding: Nonprofit institution or equivalents
- Targeting CD70-positive cancer-associated fibroblasts to improve chemotherapy and alleviate the immuno-suppressive tumor microenvironment in advanced colorectal cancer.From1 Jan 2019 → TodayFunding: Nonprofit institution or equivalents
- Developing a novel synergistic approach of chemotherapy and immunotherapy to enhance the anti-tumor immune response in non-small cell lung cancer.From1 Oct 2018 → TodayFunding: BOF - Doctoral projects (pro memore - non-attributable)
- Analysis of plasma, platelets and urine nucleic acids: the value of liquid biopsy to improve diagnosis, follow-up and monitoring of treatment response of lung cancer and pancreatic cancer patients.From1 Sep 2017 → TodayFunding: Nonprofit institution or equivalents
- Will the CD70/CD27 pathway pave the way as target for immunotherapy in colorectal cancer?From1 Jan 2017 → 30 Jun 2017Funding: Nonprofit institution or equivalents
- Translational research on the novel combination of chemotherapy and anti-CD70 immunotherapy to improve treatment outcome in non-small cell lung cancer.From1 Oct 2016 → TodayFunding: Nonprofit institution or equivalents
- Identifying rational combination therapies to overcome intrinsic and acquired resistance to EGFR-targeting agents.From1 Oct 2016 → TodayFunding: Nonprofit institution or equivalents
- Investigation of DFNA5 as potential biomarker and tumour suppressor gene in 4 solid tumour types.From1 Oct 2016 → 30 Sep 2019Funding: FWO fellowships
- Predicting immunotherapy response in elderly non-small cell lung cancer patients by zooming into protein/peptide expression patterns at the tumor cell - immune cell interaction border.From1 Jan 2016 → 31 Dec 2019Funding: Stand up against Cancer, VITO (Flemish Institute for Technological Research)
- Programmed death-1 as novel immunotherapeutic target in malignant pleural mesothelioma : investigation of cancer drug of the year 2013.From1 Jan 2015 → 31 Dec 2016Funding: Foundations, funds and other with scientific goal
Publications
1 - 10 of 153 results
- Diagnostic and clinical features of lung cancer associated with cystic airspaces(2019)Journal: Journal of Thoracic DiseaseISSN: 2072-1439Volume: 11
Authors: Annemie Snoeckx, Pieter Reyntiens, Laurens Carp, Maarten J. Spinhoven, Haroun El Addouli, Astrid Van Hoyweghen, Simon Nicolay, Paul Van Schil, Patrick Pauwels, Jan van Meerbeeck, et al.
Pages: 987 - 1004 - In vitro study of the Polo-like kinase 1 inhibitor volasertib in non-small-cell lung cancer reveals a role for the tumor suppressor p53(2019)Journal: Molecular OncologyISSN: 1574-7891Volume: 13
Authors: Jolien Van den Bossche, Christophe Deben, Ines De Pauw, Hilde Lambrechts, Christophe Hermans, Vanessa Deschoolmeester, Julie Jacobs, Pol Specenier, Patrick Pauwels, Jan Vermorken, et al.
Pages: 1196 - 1213 - Hotspot DAXX, PTCH2 and CYFIP2 mutations in pancreatic neuroendocrine neoplasms(2019)Journal: Endocrine-Related CancerISSN: 1351-0088Volume: 26
Authors: Timon Vandamme, Matthias Beyens, Gitta Boons, A. Schepers, K. Kamp, K. Biermann, Patrick Pauwels, W. W. De Herder, L. J. Hofland, Marc Peeters, et al.
Pages: 1 - 12 - Overcoming intrinsic and acquired cetuximab resistance in RAS wild-type colorectal cancer(2019)Journal: CancersVolume: 11
Authors: Ines De Pauw, Filip Lardon, Jolien Van den Bossche, Hasan Baysal, Patrick Pauwels, Marc Peeters, Jan Vermorken, An Wouters
Number of pages: 20 - Circulating cell-free DNA and RNA analysis as liquid biopsy(2019)Journal: CancersVolume: 11
Authors: Laure Sorber, Karen Zwaenepoel, Julie Jacobs, Koen De Winne, Sofie Goethals, Pablo Reclusa, Kaat Van Casteren, Elien Augustus, Filip Lardon, Geert Roeyen, et al.
Number of pages: 14 - Determination of the potential tumor-suppressive effects of Gsdme in a chemically induced and in a genetically modified intestinal cancer mouse model(2019)Journal: CancersVolume: 11
Authors: Lieselot Croes, Erik F P Fransen, Marieke Hylebos, Kimberly Buys, Christophe Hermans, Glenn Broeckx, Marc Peeters, Patrick Pauwels, Ken Op de Beeck, Guido Van Camp
Number of pages: 20 - MALDI mass spectrometry imaging linked with top-down proteomics as a tool to study the non-small-cell lung cancer tumor microenvironment(2019)Volume: 2
Authors: Eline Berghmans, Geert Van Raemdonck, Karin Schildermans, Hanny Willems, Kurt Boonen, Evelyne Maes, Inge Mertens, Patrick Pauwels, Geert Baggerman
Number of pages: 21 - $^{18}F$-HX4 hypoxia PET holds promise as a prognostic and predictive imaging biomarker in a lung cancer xenograft model treated with metformin and radiotherapy(2019)Journal: Journal of Nuclear Medicine (The)ISSN: 0161-5505Volume: 60
Authors: Sven De Bruycker, Christel Vangestel, Tim Van Den Wyngaert, Patrick Pauwels, Leonie Wyffels, Steven Staelens, Sigrid Stroobants
Pages: 34 - 40 - Large-scale analysis of DFNA5 methylation reveals its potential as biomarker for breast cancer(2018)Journal: Clinical EpigeneticsISSN: 1868-7075Volume: 10
Authors: Lieselot Croes, Matthias Beyens, Erik F P Fransen, Joe Ibrahim, Wim Vanden Berghe, Arvid Suls, Marc Peeters, Patrick Pauwels, Guido Van Camp, Ken Op de Beeck
Number of pages: 13 - Unveiling a CD70-positive subset of cancer-associated fibroblasts marked by pro-migratory activity and thriving regulatory T cell accumulation(2018)Journal: OncoimmunologyISSN: 2162-4011Volume: 7
Authors: Julie Jacobs, Vanessa Deschoolmeester, Karen Zwaenepoel, Tal Flieswasser, Christophe Deben, Jolien Van den Bossche, Christophe Hermans, Christian Rolfo, Marc Peeters, Olivier De Wever, et al.
Number of pages: 11