Publications
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Liver progenitor cell biology in chronic liver disease. Vrije Universiteit Brussel
regenerative capacity. Unfortunately, this hepatocytic regeneration does not last forever. Severe acute or chronic liver injury leads to hepatocyte senescence which results in the activation of another epithelial cell type, called a liver progenitor cell (LPC). These adult stem cells are capable to proliferate unlimited source of new liver cells. However, mechanisms involved in their differentiation and participation in liver regeneration are ...
Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure KU Leuven
Despite improvements in modern cardiovascular therapy, the morbidity and mortality of ischaemic heart disease (IHD) and heart failure (HF) remain significant in Europe and worldwide. Patients with IHD may benefit from therapies that would accelerate natural processes of postnatal collateral vessel formation and/or muscle regeneration. Here, we discuss the use of cells in the context of heart repair, and the most relevant results and current ...