Autophagy and Crohn's Disease: Towards New Therapeutic Connections KU Leuven
© 2014 Elsevier Inc. All rights reserved.. In recent years strong progress has been made in understanding the molecular basis of Crohn's disease, a multifactorial chronic inflammatory disease of the gastrointestinal tract. Recent data suggest that if autophagy, the major lysosomal pathway for recycling of cytoplasmic material, is inhibited, this may significantly contribute to an increased susceptibility for Crohn's disease. Consequently, ...