Researcher
Patrizia Agostinis
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Cell death, Cell signalling, Cancer therapy
Affiliations
- Laboratory of Cell Death Research & Therapy (VIB-KU Leuven) (Division)
Responsible
From1 Jan 2012 → Today - Agostinis Lab (Research group)
Responsible
From1 Mar 2019 → Today - Laboratory of Cell Death Research & Therapy (VIB-KU Leuven) (Division)
Member
From1 Oct 2007 → Today
Projects
1 - 10 of 57
- The lymph node pre-metastatic niche: role of the iron metabolism in the tumor invasion and on the immune microenvironmentFrom1 Oct 2023 → TodayFunding: FWO junior postdoctoral fellowship
- Harnessing lysosomal iron homeostasis to prevent melanoma disseminationFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Function of PERK in T cell metabolic reprogramming: deciphering its role as ER stress sensor vs its novel role as coordinator of membrane contact sitesFrom1 Oct 2022 → TodayFunding: FWO senior postdoctoral fellowship
- Next-generation, multi-technology immune-monitoring and easy-access spectral flow cytometryFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Understanding the spatio-temporal changes of the metastatic lymph node epicenterFrom11 Apr 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Understanding and tackling the spatio-temporal changes of the metastatic lymph node epicenterFrom1 Jan 2022 → TodayFunding: FWO EOS
- Unfolding the role of Perk in T cell biology and metabolism: a matter of contact sites?From1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- DIPITO: valorisation of deep immune profiling and novel immunotherapeutics for oncology.From1 Oct 2021 → TodayFunding: IOF - mandates
- Inter-organelle communication through membrane contact sites in oncology and neurodegenerative diseases (InterAction)From1 Oct 2021 → TodayFunding: Fund Recuperation Fiscal Exemption, BOF - projects
- Clinical, Immunological and Functional Study of ADA2 deficiencyFrom2 Aug 2021 → TodayFunding: FWO fellowships
Publications
1 - 10 of 235
- Missense variants in CMS22 patients reveal that PREPL has both enzymatic and nonenzymatic functions.(2024)
Authors: Yenthe Monnens, Alexia Mahy, Roeland Vanhoutte, Patrizia Agostinis, Steven Verhelst, John Creemers
Pages: e179276 - A deep phenotyping study in mouse and iPSC models to understand the role of oligodendroglia in optic neuropathy in Wolfram syndrome(2024)
Authors: Steven Bergmans, Patrizia Agostinis, Lieve Moons, Lies De Groef
- Correction to: Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs.(2024)
Authors: Tim Vervliet, Geert Bultynck, Patrizia Agostinis, Ludo Van Den Bosch
Pages: 99 - Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs(2024)
Authors: Yingli Zhu, Thibaut Burg, Tim Vervliet, Maria Livia Sassano, Yoke Chin Chai, Geert Bultynck, Patrizia Agostinis, Johan Swinnen, Ludo Van Den Bosch, Catherine Verfaillie
- Similar metabolic pathways are affected in both Congenital Myasthenic Syndrome-22 and Prader-Willi Syndrome(2024)
Authors: Yenthe Monnens, Lieven Thorrez, Patrizia Agostinis, Anne Rochtus, John Creemers
- An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade(2024)
Authors: Apostolis Nikolakopoulos, Francesca Bosisio, Gabriele Bergers, Colinda Scheele, Patrizia Agostinis
- Antioxidant network-based signatures cluster glioblastoma into distinct redox-resistant phenotypes(2024)
Authors: Steven De Vleeschouwer, Patrizia Agostinis
- Tumor endothelial cell autophagy is a key vascular-immune checkpoint in melanoma(2024)
Authors: Jelle Verhoeven, Patrizia Agostinis, Madhur Agrawal, Sandra Nuyts
- SECRETED APOE REWIRES MELANOMA CELL STATE VULNERABILITY TO FERROPTOSIS(2024)
Authors: Sanket More, Patrizia Agostinis
- Decoding immunogenic cell death from a dendritic cell perspective(2024)
Authors: Patrizia Agostinis
Pages: 350 - 370