Study of the intrahepatic resistance and its determinants in a rat model of severe non-alcoholic fatty liver disease (NAFLD). University of Antwerp
In our study we focus on disturbances in the liver blood flow. Previously we showed that severe steatosis leads to a significant rise in blood pressure in the portal system ("portal hypertension") preceding the occurrence of inflammation. The degreeof portal hypertension appeared to be related to the severity of steatosis. These findings points towards a significant increase in intrahepatic resistance and subsequent impairment of liver blood ...