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Researcher
Susan Schlenner
- Disciplines:Systems biology, Molecular and cell biology, Immunology
Affiliations
- Adaptive Immunology (Lab)
Responsible
From1 Jan 2019 → Today - Adaptive Immunology (Lab)
Member
From1 May 2012 → 30 Sep 2022
Infrastructure
1 - 1 of 1
- Next-generation, multi-technology immune-monitoring and easy-access spectral flow cytometry (Consortium coordinator)
Projects
1 - 10 of 26
- Validation of CCR8 agonism as therapeutic strategy for treatment of (auto-)inflammationFrom1 Mar 2024 → TodayFunding: IOF - technology validation in lab
- To be determinedFrom30 Aug 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- The Functional Characterization of Immune Cells-Astrocyte Interactions during CNS InflammationFrom16 Aug 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Study the function of short Psi in mouse and human immune cellsFrom1 May 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Unique IsoPlexis technology for multiplexed single cell functional profilingFrom1 Jan 2023 → TodayFunding: BOF - scientific equipment program
- Next-generation, multi-technology immune-monitoring and easy-access spectral flow cytometryFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Functional dissection of RNA modifiers in immune cells using CROPseqFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Role of RNA modification in immune cell functionFrom1 Oct 2021 → TodayFunding: FWO fellowships
- Spectral flowcytometry (Cytek Aurora)From1 Jan 2021 → 31 Dec 2022Funding: BOF - scientific equipment program
- ”RNA modifications: new mechanisms to regulate immune homeostasis and function”From1 Oct 2020 → TodayFunding: BOF - projects
Publications
31 - 40 of 44
- Regulatory T cell differentiation: cooperation saves the day(2015)
Authors: Adrian Liston, Susan Schlenner
Pages: 1145 - 6 - Promiscuous Foxp3-cre activity reveals a differential requirement for CD28 in Foxp3(+) and Foxp3(-) T cells(2015)
Authors: Dean Franckaert, James Dooley, Evelyne Roos, Adrian Liston, Susan Schlenner
Pages: 417 - 23 - Fundamental properties of unperturbed haematopoiesis from stem cells in vivo(2015)
Authors: Susan Schlenner
Pages: 542 - 546 - The thymic microenvironment differentially regulates development and trafficking of invariant NKT cell sublineages(2014)
Authors: Susan Schlenner
Pages: 5960 - 5972 - The Thymic Microenvironment Differentially Regulates Development and Trafficking of Invariant Natural Killer T Cell Sublineages(2014)
Authors: Michael B Drennan, Srinath Govindarajan, Katelijne De Wilde, Susan Schlenner, Carl Ware, Sergei Nedospasov, Hans-Reimer Rodewald, Dirk Elewaut
Pages: 220 - 220 - A ZAP-70 kinase domain variant prevents thymocyte positive selection despite signalling CD69 induction(2014)
Authors: Susan Schlenner, Adrian Liston
Pages: 587 - 95 - A novel Zap70 mutation with reduced protein stability demonstrates the rate-limiting threshold for Zap70 in T cell receptor signalling(2014)
Authors: Bénédicte Cauwe, Lei Tian, Dean Franckaert, Wim Pierson, Kim Staats, Susan Schlenner, Adrian Liston
Pages: 377 - 87 - Mast cell chymase degrades the alarmins heat shock protein 70, biglycan, HMGB1, and interleukin-33 (IL-33) and limits danger-induced inflammation(2014)
Authors: Susan Schlenner
Pages: 237 - 250 - Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3(+) regulatory T cells(2013)
Authors: Wim Pierson, Bénédicte Cauwe, Susan Schlenner, Dean Franckaert, Stephanie Humblet-Baron, Patrick Matthys, James Dooley, Adrian Liston
Pages: 959 - 65 - Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut(2012)
Authors: Susan Schlenner
Pages: 1529 - 35