Researcher
Peter Tompa
- Research Expertise
(Vrije Universiteit Brussel):
intrinsically disordered protein
structural biology
liquid-liquid phase separation
- Keywords (Vrije Universiteit Brussel):Applied biological sciences, biotechnology
- Disciplines (Flanders Institute for Biotechnology):(Bio)molecular modelling and design, Analytical biochemistry, Medical biophysics
- Disciplines (Vrije Universiteit Brussel):Intracellular compartments and transport
- Users of research expertise
(Vrije Universiteit Brussel):
intrinsically disordered protein
structural biology
liquid-liquid phase separation
- See also: Peter Tompa (Flanders Institute for Biotechnology)
Affiliations
- Department of Bio-engineering Sciences (Department)
Member
From8 Apr 2019 → Today - Tompa Lab (Research group)
Responsible
From1 Jan 2017 → Today - Department of Bio-engineering Sciences (Department)
Member
From1 Oct 2011 → 20 Oct 2022 - Structural Biology Brussels (Research group)
Member
From1 May 2011 → 31 Mar 2024 - Department of Bio-engineering Sciences (Department)
Member
From1 May 2011 → 30 Sep 2021 - Department of Bio-engineering Sciences (Department)
Member
From1 May 2011 → 30 Sep 2014
Projects
1 - 9 of 9
- Characterizing mutations in hnRNPA2 to identify pathogenic mechanisms in degenerative disordersFrom1 Nov 2022 → TodayFunding: FWO fellowships
- Uncovering the effect of long non-coding RNAs on liquid-liquid phase separation of androgen receptor in prostate cancerFrom1 Nov 2022 → TodayFunding: FWO fellowships
- Backup mandate Research Council: Exploring prion-like nucleation of liquid-liquid phase separation of hnRNPA2 in Amyotrophic Lateral SclerosisFrom1 Nov 2021 → 31 Oct 2022Funding: BOF - doctoral mandates
- Unravelling the molecular mechanism of animal adhesive secretions to widen the horizons for new bio-inspired materials.From1 Nov 2019 → 31 Oct 2023Funding: FWO fellowships
- Targeting the interaction of menin and androgen receptor (AR) for developing new drugs against prostate cancerFrom1 Nov 2019 → 18 Sep 2023Funding: FWO fellowships
- Role of ubiquitination in phase transitions in Amyotrophic Lateral Sclerosis (ALS)From1 Nov 2019 → 31 Jan 2024Funding: FWO fellowships
- SRP-Onderzoekszwaartepunt: Optical and microfluidic tools to unravel the dynamics of bio-condensatesFrom1 Mar 2019 → 29 Feb 2024Funding: BOF - projects
- Structural biology of large and flexible macromolecules in solution: Small angle X-Ray Scatter (Bio-SAXS) and Multi-angle light scatter (MALS) (UABR/11/012)From19 Nov 2012 → 24 Apr 2017Funding: Hercules - Small and Medium size research infrastructure
- In vitro cell-free protein synthesis and purification platform.From26 Apr 2012 → 25 Apr 2017Funding: Hercules - Small and Medium size research infrastructure
Publications
11 - 20 of 90
- Degron masking outlines degronons, co-degrading functional modules in the proteome(2022)
Authors: Mainak Guharoy, Mauricio Macossay Castillo, Peter Tompa
- Exploring curated conformational ensembles of intrinsically disordered proteins in the Protein Ensemble Database(2021)
Authors: Federica Quaglia, Tamas Lazar, András Hatos, Peter Tompa, Damiano Piovesan, Silvio C E Tosatto
- DNA-binding domain as the minimal region driving RNA-dependent liquid-liquid phase separation of androgen receptor(2021)
Authors: Junaid Ahmed, Attila Meszaros, Tamas Lazar, Peter Tompa
Pages: 1380-1392 - Critical assessment of protein intrinsic disorder prediction(2021)
Authors: Marco Necci, Damiano Piovesan, Gabriele Orlando, Daniele Raimondi, Mauricio Macossay Castillo, Mainak Guharoy, Peter Tompa, Silvio C E Tosatto
Pages: 472-481 - Liquid-Liquid Phase Separation Enhances TDP-43 LCD Aggregation but Delays Seeded Aggregation(2021)
Authors: Donya Pakravan, Emiel Michiels, Anna Bratek-Skicki, Mathias De Decker, Joris Van Lindt, David Alsteens, Sylvie Derclaye, Philip Van Damme, Joost Schymkowitz, Frederic Rousseau, et al.
- Integration of Data from Liquid–Liquid Phase Separation Databases Highlights Concentration and Dosage Sensitivity of LLPS Drivers(2021)
Authors: Nazanin Farahi, Tamas Lazar, Shoshana Wodak, Peter Tompa, Rita Anna Pancsa
Pages: 1-26 - A generic approach to study the kinetics of liquid–liquid phase separation under near-native conditions(2021)
Authors: Joris Van Lindt, Anna Bratek-Skicki, Phuong N Nguyen, Donya Pakravan, Luis Fernando Duran Armenta, Agnes Tantos, Rita Anna Pancsa, Ludo Van Den Bosch, Dominique Maes, Peter Tompa
- PED in 2021: a major update of the Protein Ensemble Database for intrinsically disordered proteins(2021)
Authors: Tamas Lazar, Elizabeth Martinez-Perez, Federica Quaglia, András Hatos, Lucia Chemes, Javier Iserte, Nicolás Méndez, Nicolás Garrone, Tadeo Saldaño, Julia Marchetti, et al.
Pages: D404-D411 - Chasing coevolutionary signals in intrinsically disordered proteins complexes(2020)
Authors: Javier Iserte, Tamas Lazar, Silvio C E Tosatto, Peter Tompa, Cristina Marino-Buslje
- Interplay of Structural Disorder and Short Binding Elements in the Cellular Chaperone Function of Plant Dehydrin ERD14(2020)
Authors: Nikoletta Murvai, Lajos Kalmar, Bianka Szalaine Agoston, Beata Szabo, Agnes Tantos, Gyorgy Csikos, András Micsonai, József Kardos, Didier Vertommen, Phuong N Nguyen, et al.
Pages: 1-20