Researcher
Peter Tompa
- Research Expertise
(Vrije Universiteit Brussel):
intrinsically disordered protein
structural biology
liquid-liquid phase separation
- Keywords (Vrije Universiteit Brussel):Applied biological sciences, biotechnology
- Disciplines (Flanders Institute for Biotechnology):(Bio)molecular modelling and design, Analytical biochemistry, Medical biophysics
- Disciplines (Vrije Universiteit Brussel):Intracellular compartments and transport
- Users of research expertise
(Vrije Universiteit Brussel):
intrinsically disordered protein
structural biology
liquid-liquid phase separation
- See also: Peter Tompa (Flanders Institute for Biotechnology)
Affiliations
- Department of Bio-engineering Sciences (Department)
Member
From8 Apr 2019 → Today - Tompa Lab (Research group)
Responsible
From1 Jan 2017 → Today - Department of Bio-engineering Sciences (Department)
Member
From1 Oct 2011 → 20 Oct 2022 - Structural Biology Brussels (Research group)
Member
From1 May 2011 → 31 Mar 2024 - Department of Bio-engineering Sciences (Department)
Member
From1 May 2011 → 30 Sep 2021 - Department of Bio-engineering Sciences (Department)
Member
From1 May 2011 → 30 Sep 2014
Projects
1 - 9 of 9
- Characterizing mutations in hnRNPA2 to identify pathogenic mechanisms in degenerative disordersFrom1 Nov 2022 → TodayFunding: FWO fellowships
- Uncovering the effect of long non-coding RNAs on liquid-liquid phase separation of androgen receptor in prostate cancerFrom1 Nov 2022 → TodayFunding: FWO fellowships
- Backup mandate Research Council: Exploring prion-like nucleation of liquid-liquid phase separation of hnRNPA2 in Amyotrophic Lateral SclerosisFrom1 Nov 2021 → 31 Oct 2022Funding: BOF - doctoral mandates
- Targeting the interaction of menin and androgen receptor (AR) for developing new drugs against prostate cancerFrom1 Nov 2019 → 18 Sep 2023Funding: FWO fellowships
- Unravelling the molecular mechanism of animal adhesive secretions to widen the horizons for new bio-inspired materials.From1 Nov 2019 → 31 Oct 2023Funding: FWO fellowships
- Role of ubiquitination in phase transitions in Amyotrophic Lateral Sclerosis (ALS)From1 Nov 2019 → 31 Jan 2024Funding: FWO fellowships
- SRP-Onderzoekszwaartepunt: Optical and microfluidic tools to unravel the dynamics of bio-condensatesFrom1 Mar 2019 → 29 Feb 2024Funding: BOF - projects
- Structural biology of large and flexible macromolecules in solution: Small angle X-Ray Scatter (Bio-SAXS) and Multi-angle light scatter (MALS) (UABR/11/012)From19 Nov 2012 → 24 Apr 2017Funding: Hercules - Small and Medium size research infrastructure
- In vitro cell-free protein synthesis and purification platform.From26 Apr 2012 → 25 Apr 2017Funding: Hercules - Small and Medium size research infrastructure
Publications
21 - 30 of 90
- Distance-Based Metrics for Comparing Conformational Ensembles of Intrinsically Disordered Proteins(2020)
Authors: Tamas Lazar, Mainak Guharoy, Wim Vranken, Sarah Rauscher, Shoshana Wodak, Peter Tompa
Pages: 2952-2965 - A Guide to Regulation of the Formation of Biomolecular Condensates.(2020)
Authors: Anna Bratek-Skicki, Rita Pancsa, Balint Mészáros, Joris Van Lindt, Peter Tompa
Pages: 1924-1935 - Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity(2020)
Authors: Simone Kosol, Sara Contreras Martos, Alessandro Piai, Mihály Váradi, Tamas Lazar, Angela Bekesi, Pierre Lebrun, Isabella C Felli, Roberta Pierattelli, Peter Tompa
- DisProt: intrinsic protein disorder annotation in 2020(2020)
Authors: András Hatos, Borbala Hajdu-Soltesz, Alexander Miguel Monzon, Nicolas Palopoli, Lucia Alvarez, Burcu Aykac-Fas, Claudio Bassot, Guillermo Ignacio Benitez, Martina Bevilacqua, Anastasia Chasapi, et al.
Pages: D269-D276 - Validation of in silico design and covalent modification of intrinsically disordered proteins(2020)
Authors: Huy Hung Nguyen, Peter Tompa
- The interplay between multifunctionality and protein intrinsic disorder(2020)
Authors: Mauricio Macossay Castillo, Peter Tompa
- In silico analysis of short linear peptide motifs in intrinsically disordered proteins(2020)
Authors: Tamas Lazar, Peter Tompa
- An intrinsically disordered proteins community for ELIXIR(2019)
Authors: Norman E Davey, Madan Babu, Martin Blackledge, Alan Bridge, Salvador Capella-Gutierrez, Zsuzsanna Dosztanyi, Rachel Drysdale, Richard J Edwards, Arne Elofsson, Isabella C Felli, et al.
- Focusing of Microcrystals and Liquid Condensates in Acoustofluidics(2019)
Authors: Pierre Gelin, Joris Van Lindt, Anna Bratek-Skicki, Iwona Ziemecka, Sander Stroobants, Marzena Krzek, Peter Tompa, Wim De Malsche, Dominique Maes
- The Balancing Act of Intrinsically Disordered Proteins: Enabling Functional Diversity while Minimizing Promiscuity(2019)
Authors: Mauricio Macossay Castillo, Giulio Marvelli, Mainak Guha Roy, Aashish Jain, Daisuke Kihara, Peter Tompa, Shoshana Wodak
Pages: 1650-1670