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Researcher
Patrick Augustijns
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences
Affiliations
- Drug Delivery and Disposition (Division)
Member
From1 Oct 1999 → Today
Projects
31 - 40 of 43
- The effect of chronic kidney disease on production, intestinal absorption and renal excretion of microbiome metabolites. Exploring the gut-kidney axis.From1 Oct 2012 → 30 Sep 2016Funding: FWO fellowships
- Influence of Obesity and Gastric Bypass on Medication Absorption.From1 Oct 2011 → 30 Sep 2015Funding: IWT personal funding - strategic basic research grants
- Development, validation and application of complementary in vitro models for the prediction of in vivo clearance of drug candidates in specific populations.From1 Oct 2011 → 18 Feb 2016Funding: IWT personal funding - strategic basic research grants
- In-depth understanding of crystallization inhibition by polymers during dissolution of amorphous drugs to maximize absorption and bioavailability.From1 Oct 2010 → 30 Sep 2013Funding: FWO fellowships
- Development of novel in vitro and in vivo model systems to study intravaginal microbicide behavior.From1 Oct 2010 → 15 Oct 2014Funding: FWO fellowships
- CHAARM. Combined Highly Active Anti-retroviral Microbicides.From1 Jan 2010 → 30 Jun 2015Funding: General Activities (Annex IV)
- Intestinal perfusion with mesenteric blood sampling in mice as an innovative biopharmaceutical drug evaluation tool.From1 Jan 2010 → 31 Dec 2013Funding: FWO research project (including WEAVE projects)
- Chemotherapy during pregnancy: A pharmacokinetic and placenta studyFrom1 Jan 2010 → 1 Sep 2012Funding: Own budget, for example: patrimony, inscription fees, gifts
- In vivo evaluation and in vitro prediction of the performance of supersaturating drug delivery systems in the gastrointestinal environment.From1 Oct 2009 → 30 Sep 2012Funding: FWO fellowships
- Development and integrated use of novel preclinical models to assess intestinal absorption and hepatic elimination in order to achieve accelerated biopharmaceutical drug profiling.From1 Oct 2009 → 5 Oct 2014Funding: BOF - Concerted Research Project from 1994
Publications
1 - 10 of 377
- Corrigendum to "The effect of esomeprazole on the upper GI tract release and systemic absorption of mesalazine from colon targeted formulations" [Int. J. Pharm. 619 (2022) 121701].(2024)
Authors: Joachim Brouwers, Patrick Augustijns
Pages: 124087 - Expression of intestinal drug transporter proteins and metabolic enzymes in neonatal and pediatric patients.(2024)
Authors: Joachim Brouwers, Marc Miserez, Maissa Rayyan, Patrick Augustijns
Pages: 123962 - Understanding the gastrointestinal tract in obesity: From gut motility patterns to enzyme secretion(2024)
Authors: Nele Steenackers, Gabriël Johannes Eksteen, Lucas Wauters, Patrick Augustijns, Bart Van Der Schueren, Tim Vanuytsel, Christophe Matthys
- Tofacitinib in Pregnancy: Assessing Pregnancy and Infant Outcomes, Cord Blood, and Breast Milk Concentrations.(2024)
Authors: Patrick Augustijns
Pages: S1542-3565 - Enzymatic prodrug degradation in the fasted and fed small intestine: In vitro studies and interindividual variability in human aspirates(2024)
Authors: Patrick Augustijns
- The Dynamic Intestinal Absorption Model (Diamod®), an in vitro tool to study the interconnected kinetics of gastrointestinal solubility, supersaturation, precipitation, and intestinal permeation processes of oral drugs(2023)
Authors: Patrick Augustijns
- Development and complications of nutritional deficiencies after bariatric surgery(2023)
Authors: Nele Steenackers, Bart Van Der Schueren, Patrick Augustijns, Tim Vanuytsel, Christophe Matthys
- Drug Dissolution in Oral Drug Absorption: Workshop Report(2023)
Authors: Patrick Augustijns
- Approaches to Account for Colon Absorption in Physiologically Based Biopharmaceutics Modeling of Extended-Release Drug Products(2023)
Authors: Harshad Sunil Jadhav, Patrick Augustijns
Pages: 6272 - 6288 - Challenges in Permeability Assessment for Oral Drug Product Development(2023)
Authors: Patrick Augustijns
Patents
1 - 1 of 1
- Permeability model (Inventor)