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Researcher
Patrick Augustijns
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences
Affiliations
- Drug Delivery and Disposition (Division)
Member
From1 Oct 1999 → Today
Projects
11 - 20 of 43
- Drug Absorption in Geriatric Patients and Older People: a training network innovating drug development for the advanced age populationFrom1 Jan 2021 → TodayFunding: H2020 - Skills and Career Development (Marie Skłodowska-Curie) actions
- Drug solubility in human intestinal fluids: multi-objective analysis and modellingFrom1 Oct 2020 → 30 Sep 2022Funding: BOF - projects
- Pediatric biopharmaceutics: translating gastrointestinal characteristics into improved predictive absorption tools.From1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- Towards a deeper understanding of physiological factors affecting drug and formulation behavior in the human gastrointestinal tractFrom1 Oct 2018 → 2 Nov 2020Funding: FWO fellowships
- Oral drug absorption in specific patient populations: understanding the impact of gastrointestinal physiologyFrom1 Oct 2018 → 21 Jun 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Exploring physiological factors affecting drug and formulation behavior in the human gastrointestinal tractFrom1 Jan 2018 → 31 Dec 2018Funding: BOF - Other initiatives
- Intestinal drug absorption: what is happening inside and beyond.From1 Dec 2017 → 30 Apr 2018Funding: H2020 - European Institute of Innovation and Technology
- Developing in vitro models mimicking the upper GI-tract after RYGB and SG to simulate the digestibility and absorption of nutritional supplements and tailored foodsFrom1 Oct 2017 → 31 Mar 2021Funding: IOF - Industrial Research Fund
- Improving insight into colonic drug disposition for the development of predictive tools.From1 Oct 2017 → 30 Sep 2021Funding: IOF - Industrial Research Fund
- Impact of the dynamic nature of the human gastrointestinal tract on drug and formulation behavior.From1 Jan 2017 → 31 Dec 2020Funding: FWO research project (including WEAVE projects)
Publications
1 - 10 of 373
- Expression of intestinal drug transporter proteins and metabolic enzymes in neonatal and pediatric patients.(2024)
Authors: Joachim Brouwers, Marc Miserez, Maissa Rayyan, Patrick Augustijns
Pages: 123962 - Enzymatic prodrug degradation in the fasted and fed small intestine: In vitro studies and interindividual variability in human aspirates(2024)
Authors: Patrick Augustijns
- The Dynamic Intestinal Absorption Model (Diamod®), an in vitro tool to study the interconnected kinetics of gastrointestinal solubility, supersaturation, precipitation, and intestinal permeation processes of oral drugs(2023)
Authors: Patrick Augustijns
- Development and complications of nutritional deficiencies after bariatric surgery(2023)
Authors: Nele Steenackers, Bart Van Der Schueren, Patrick Augustijns, Tim Vanuytsel, Christophe Matthys
- Drug Dissolution in Oral Drug Absorption: Workshop Report(2023)
Authors: Patrick Augustijns
- Approaches to Account for Colon Absorption in Physiologically Based Biopharmaceutics Modeling of Extended-Release Drug Products(2023)
Authors: Harshad Sunil Jadhav, Patrick Augustijns
Pages: 6272 - 6288 - Challenges in Permeability Assessment for Oral Drug Product Development(2023)
Authors: Patrick Augustijns
- Investigating Tacrolimus Disposition in Paediatric Patients with a Physiologically Based Pharmacokinetic Model Incorporating CYP3A4 Ontogeny, Mechanistic Absorption and Red Blood Cell Binding(2023)
Authors: Joachim Brouwers, Patrick Augustijns
- Physiologically based pharmacokinetic (PBPK) modelling of oral drug absorption in older adults-an AGePOP review(2023)
Authors: Jos Tournoy, Patrick Augustijns
- The impact of advanced age on gastrointestinal characteristics that are relevant to oral drug absorption: An AGePOP review(2023)
Authors: Gabriël Johannes Eksteen, Fritz Harder, Patrick Augustijns, Christophe Matthys
Patents
1 - 1 of 1
- Permeability model (Inventor)