Researcher
Luc Leybaert
- Disciplines:Inflammation, Cell death, Cell therapy
Affiliations
- Department of Basic and Applied Medical Sciences (Department)
Member
From1 Oct 2018 → Today - Department of Basic Medical Sciences (Department)
Member
From1 Oct 2008 → 30 Sep 2018 - Department of General physiology and human physiology and pathophysiology (Department)
Member
From1 Jan 1993 → 30 Sep 2008
Projects
1 - 10 of 37
- Impact of peripheral virus infection on the central nervous systemFrom1 Jan 2023 → TodayFunding: BOF - projects
- CONNEXIN-43 HEMICHANNELS AS PRO-ARRHYTHMIC MEDIATORS IN CARDIAC HYPERTROPHY AND HEART FAILUREFrom1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Cofunding core facility - Ghent Light Microscopy (GLiM)From1 Jul 2022 → TodayFunding: BOF - research organisations
- White light laser-based confocal fluorescence lifetime imaging microscope for multi-parameter 3D live imagingFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Long-term live cell imaging of intracellular signals and cell death.From1 Dec 2020 → 30 Nov 2022Funding: BOF - scientific equipment program
- Stimulated emission depletion microscopy (STED): Nanoscopy for innovative research in the life sciencesFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Blood-brain barrier disturbances in response to ionizing radiation: role of connexin/calcium bystander signalingFrom1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- Controlled delivery of connexin43 mimetic peptide by nanocontainers for therapy of systemic inflammationFrom1 Oct 2018 → 31 Jul 2023Funding: BOF - Doctoral projects
- Combined single-channel electrophysiology and fluorescence microscopy for fundamental studies of ion channel functionFrom1 Jun 2018 → 31 May 2020Funding: BOF - Other initiatives
- Basic investigations on the role of connexin hemichannels as an arrhythmogenic substrate in ventricular arrhythmiaFrom1 Jan 2018 → 31 Dec 2021Funding: FWO research project (including WEAVE projects)
Publications
41 - 50 of 195
- The BH4 domain of Bcl-2 orthologues from different classes of vertebrates can act as an evolutionary conserved inhibitor of IP3 receptor channels(2017)
Authors: Hristina Ivanova, Thomas Luyten, Tim Vervliet, Luc Leybaert, Jan B Parys, Geert Bultynck
Pages: 41 - 46 - Inhibition of connexin hemichannels alleviates non-alcoholic steatohepatitis in mice(2017)
Authors: Joost Willebrords, Bruno Cogliati, Isabel Veloso Alves Pereira, Tereza Cristina da Silva, Sara Crespo Yanguas, Michaël Maes, Veronica Mollica Govoni, Andressa Lima, Daniele Aparecida Felisbino, Marina Sayuri Nogueira, et al.
- Mitochondrial Cx43 hemichannels contribute to mitochondrial calcium entry and cell death in the heart(2017)
Authors: Ashish Kumar Gadicherla, Nan Wang, Marco Bulic, Esperanza Agullo-Pascual, Alessio Lissoni, Mario Delmar, Geert Bultynck, Amadou Camara, Klaus-Dieter Schlüter, Rainer Schulz, et al.
- Calcium, oxidative stress and connexin channels, a harmonious orchestra directing the response to radiotherapy treatment?(2017)
Authors: Delphine Hoorelbeke, Raghda Ramadan, Tinneke Delvaeye, Marijke De Bock, Nan Wang, Sarah Baatout, Geert Bultynck, An Aerts, Mathieu Vinken, Luc Leybaert
Pages: 1099 - 1120 - Whole-cell patch clamp recordings of unitary connexin 43 hemichannel currents(2016)Series: Methods in signal Transduction Series
Authors: Nan Wang, Alessio Lissoni, Maarten De Smet, Karin R Sipido, Luc Leybaert, Donglin Bai, Juan Sáez
Pages: 189 - 201 - Nutrient starvation decreases Cx43 levels and limits intercellular communication in primary bovine corneal endothelial cells(2016)
Authors: Catheleyne D'hondt, Jegan Iyyathurai, Kirsten Welkenhuyzen, Bernard Himpens, Luc Leybaert, Geert Bultynck
Pages: 363 - 373 - Into rather unexplored terrain : transcellular transport across the blood-brain barrier(2016)
Authors: Marijke De Bock, Valérie Van Haver, Nan Wang, Luc Leybaert
Pages: 1097 - 1123 - Zinc chelation promotes oocyte activation in human oocytes(2016)Volume: 31
Authors: Davina Bonte, Minerva Ferrer Buitrago, Margot Van der Jeught, Dieter Deforce, Luc Leybaert
Pages: 236 - 236 - Connexins : substrates and regulators of autophagy(2016)
Authors: Jegan Iyyathurai, Jean-Paul Decuypere, Luc Leybaert, Catheleyne D'hondt, Geert Bultynck
- IP3, still on the move but now in the slow lane(2016)
Authors: Luc Leybaert
Patents
1 - 3 of 3