Researcher
Johan Swinnen
- Disciplines:Oncology, Medical systems biology
Affiliations
- Laboratory of Lipid Metabolism and Cancer (Division)
Responsible
From1 Jan 2012 → Today - Laboratory of Lipid Metabolism and Cancer (Division)
Member
From1 Jan 2012 → Today - Clinical and Experimental Endocrinology (Division)
Member
From1 Jan 2003 → 31 Dec 2011 - Department of Development and Regeneration (Department)
Member
From1 Oct 2000 → 31 Dec 2002
Infrastructure
1 - 2 of 2
- An high-throughput automated small molecule screening platform (Consortium coordinator)
- Next Generation Magnetic Resonance Mass Spectrometry. (Consortium coordinator)
Projects
1 - 10 of 51
- Targeting lipid metabolism to overcome cancer therapy resistanceFrom1 Apr 2024 → TodayFunding: IOF - mandates
- Een uitgebreide pijplijn voor translationeel onderzoek en training die het lipidenmetabolisme benut om de behandeling van prostaatkanker te verbeteren en jonge onderzoekers op te leiden in de aanpak van complexe ziektenFrom1 Jan 2024 → TodayFunding: HORIZON.1.2 - Marie Skłodowska-Curie-actions (MSCA)
- A Comprehensive Translational Research and Training Pipeline Harnessing Lipid Metabolism to Improve Prostate Cancer Management and Educate Young Researchers in Tackling Complex DiseaseFrom1 Jan 2024 → TodayFunding: BOF - projects
- Chemical Imaging of Biological Systems by Mass Spectrometry Imaging-enhanced Coherent Raman Scattering MicroscopyFrom2 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- 4D-Lipidomics: a new standard in advanced lipidomics researchFrom1 Jan 2023 → TodayFunding: BOF - scientific equipment program
- LipoMacs: functional Lipidomics to unlock Macrophage-mediated therapyFrom1 Oct 2022 → TodayFunding: FWO Strategic Basic Research (SBO)
- Multimodal Coherent Raman Scattering /Fluorescence Lifetime Imaging Microscopy systemFrom2 Aug 2022 → TodayFunding: Other federal scientific institutions
- An high-throughput automated small molecule screening platform.From1 May 2022 → TodayFunding: FWO Large scale research infrastructure
- Aggressive salivary gland neoplasms: institutional-international collaborative evaluation of advances in clinical management and translational research into tumor biologyFrom11 Jan 2022 → 31 Dec 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Inter-organelle communication through membrane contact sites in oncology and neurodegenerative diseases (InterAction)From1 Oct 2021 → TodayFunding: Fund Recuperation Fiscal Exemption, BOF - projects
Publications
41 - 50 of 133
- BNIP3 promotes HIF-1α-driven melanoma growth by curbing intracellular iron homeostasis(2021)
Authors: Matteo Rossi, Chris Van den Haute, Maria Livia Sassano, Abhishek Garg, Francesca Bosisio, Jasper Wouters, Peter Vangheluwe, Wim Annaert, Johan Swinnen, Joost van den Oord, et al.
- Fat Induces Glucose Metabolism in Nontransformed Liver Cells and Promotes Liver Tumorigenesis(2021)
Authors: Lindsay Broadfield, dorien Broekaert, Koen Veys, Roman Vangoitsenhoven, Jonas Dehairs, James Dooley, Jos van Pelt, Adrian Liston, Chantal Mathieu, Christophe Deroose, et al.
Pages: 1988 - 2001 - Removal of optimal cutting temperature (OCT) compound from embedded tissue for MALDI imaging of lipids(2021)
Authors: Xander Spotbeen, Johan Swinnen
Pages: 2695 - 2708 - ELOVL5 Is a Critical and Targetable Fatty Acid Elongase in Prostate Cancer(2021)
Authors: Jonas Dehairs, Etienne Waelkens, Rita Derua, Johan Swinnen
Pages: 1704 - 1718 - FO-SPR biosensor calibrated with recombinant extracellular vesicles enables specific and sensitive detection directly in complex matrices(2021)
Authors: Yagmur Yildizhan, Sam Noppen, Filip Delport, Dominique Schols, Johan Swinnen, Jeroen Lammertyn, Dragana Spasic
- Synthesis and fluorine-18 radiolabeling of a phospholipid as a PET imaging agent for prostate cancer(2021)
Authors: Jonas Dehairs, Johan Swinnen
Pages: 37 - 45 - ATP13A3 is a major component of the enigmatic mammalian polyamine transport system(2021)
Authors: Norin Hamouda, Chris Van den Haute, Roeland Vanhoutte, Johan Swinnen, Patrizia Agostinis, Veerle Baekelandt, Wim Annaert, Steven Verhelst, Jan Eggermont, Peter Vangheluwe
- Ceramide analog [18F]F-HPA-12 detects sphingolipid disbalance in the brain of Alzheimer's disease transgenic mice by functioning as a metabolic probe(2020)
Authors: Etienne Waelkens, Rita Derua, Johan Swinnen, Jonas Dehairs
- The use of metabonomics and lipidomics in the discovery of new actionable vulnerabilities in BRAF-mutated melanoma(2020)
Authors: Corentin Schepkens, Johan Swinnen
- Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to Protect prostate tumor cells from ferroptosis(2020)
Authors: Jonas Dehairs, Johan Swinnen
Patents
1 - 5 of 5
- Screening methods for compounds modulating polyamine transport (Inventor)
- Combination treatment of arsenic oxide and antiandrogens (Inventor)
- Cancer phospholipidome (Inventor)
- CANCER PHOSPHOLIPIDOME (Inventor)
- PHOSPHOLIPID PROFILING OF CANCER (Inventor)