Researcher
Jan Tavernier
- Disciplines:Cell signalling
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Department of Biochemistry (Department)
Responsible
From1 Oct 2010 → 30 Sep 2018 - Department of Biochemistry (Department)
Member
From1 Oct 2010 → 30 Sep 2018 - Department of Biochemistry (Department)
Member
From1 Oct 1996 → 30 Sep 2018
Projects
1 - 10 of 35
- in vivo induction of tolerogenic Dentritic cells via targeting with AcTaferonFrom1 Jan 2019 → 31 Dec 2020
- Investigation into the efficacy of IL-1b AcTaleukins as adjuvant for cancer immunotherapy.From1 Jan 2018 → 31 Dec 2021Funding: FWO research project (including WEAVE projects)
- Viral interference with RNA sensing and processingFrom1 Jan 2018 → 31 Dec 2021Funding: FWO EOS
- The impact of glucocorticoid receptor-mediated signaling on the functioning of metabolically stressed mature human adipocytesFrom1 Jan 2018 → 31 Dec 2018Funding: FWO research grant KAN
- Study of the interactions between the hepatitis E virus and its hostFrom1 Oct 2017 → 30 Sep 2021Funding: BOF - Doctoral projects
- Faster mapping of cancer driver mutations in new protein-protein
interaction interfacesFrom1 Jan 2017 → 31 Dec 2020Funding: FWO Strategic Basic Research Grant
- ACT: AcTakine-based Cancer TherapyFrom1 Oct 2015 → 30 Sep 2018Funding: BOF - Other initiatives
- AcTakines: old monkeys new tricksFrom1 Jan 2014 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- Unraveling IRE1 endonuclease activity and its role in
regulating cell fate: an interactomics approach.From1 Oct 2013 → 30 Jun 2014Funding: FWO fellowships, BOF - Other initiatives
- ERC Professorship: CYREFrom1 Oct 2013 → 30 Sep 2019Funding: BOF - ZAP BOF mandates
Publications
1 - 10 of 168
- A bispecific Clec9A-PD-L1 targeted type I interferon profoundly reshapes the tumor microenvironment towards an antitumor state(2023)
Authors: Sandra Van Lint, Alexander Van Parys, Bram Van Den Eeckhout, Niels Vandamme, Stephane Plaisance, Annick Verhee, Dominiek Catteeuw, Elke Rogge, Jennifer De Geest, Nele Vanderroost, et al.
- An unexpected encounter : respiratory syncytial virus nonstructural protein 1 interacts with mediator subunit MED25(2022)
Authors: Tessa Van Royen, Georgios Moschonas, Wendy Toussaint, M Vuylsteke, Irma Lemmens, Jan Tavernier
- Direct and indirect anti-leukemic properties of Activity-on-Target interferons for the treatment of T-cell acute lymphoblastic leukemia(2022)
Authors: Renate De Smedt, Willem Daneels, Pieter Van Vlierberghe, Jan Tavernier
Pages: 1448 - 1453 - Selective IL-1 activity on CD8+ T cells empowers antitumor immunity and synergizes with neovasculature-targeted TNF for full tumor eradication(2021)
Authors: Bram Van Den Eeckhout, Stéphane Plaisance, Gilles Uzé, Niko Kley, Jan Tavernier
- Prolyl endopeptidase-like is a (thio)esterase involved in mitochondrial respiratory chain function(2021)
Authors: Karen Rosier, Molly T. McDevitt, Joél Smet, Brendan J. Floyd, Maxime Verschoore, Maria J. Marcaida, Craig A. Bingman, Irma Lemmens, Matteo Dal Peraro, Jan Tavernier, et al.
- Targeting IFN activity to both B cells and plasmacytoid dendritic cells induces a robust tolerogenic response and protection against EAE(2021)
Authors: Anje Cauwels, Elke Rogge, Shengru Pang, Marco Prinz, Niko Kley, Gilles Uze, Jan Tavernier
- Interleukin-1 as innate mediator of T cell immunity(2021)
Authors: Bram Van Den Eeckhout, Jan Tavernier
- ZBTB32 performs crosstalk with the glucocorticoid receptor and is crucial in glucocorticoid responses to starvation(2021)
Authors: Lise Van Wyngene, Tineke Vanderhaeghen, Steven Timmermans, Katrien Corbeels, Bart Van der Schueren, Jolien Vandewalle, Kelly Van Looveren, Charlotte Wallaeys, Melanie Eggermont, Sylviane Dewaele, et al.
- Specific targeting of IL-1β activity to CD8+ T cells allows for safe use as a vaccine adjuvant(2020)
Authors: Bram Van Den Eeckhout, Lien Van Hoecke, Niko Kley, Gilles Uzé, Jan Tavernier
- Rapid and effective generation of nanobody based CARs using PCR and Gibson Assembly(2020)
Authors: Stijn De Munter, Alexander Van Parys, Layla Bral, Joline Ingels, Glenn Goetgeluk, Sarah Bonte, Melissa Pille, Lore Billiet, Karin Weening, Annick Verhee, et al.
Patents
1 - 10 of 10
- TARGETED MUTANT INTERFERON-GAMMA AND USES THEREOF (Inventor)
- IMMUNE-CELL TARGETED BISPECIFIC CHIMERIC PROTEINS AND USES THEREOF (Inventor)
- CD8 BINDING AGENTS (Inventor)
- MODULATION OF DENDRITIC CELL LINEAGES (Inventor)
- TARGETED MUTANT INTERFERON-GAMMA AND USES THEREOF (Inventor)
- BI-FUNCTIONAL CHIMERIC PROTEINS AND USES THEREOF (Inventor)
- CLEC9A BINDING AGENTS AND USE THEREOF (Inventor)
- TARGETED MUTANT INTERFERON-β USES THEREOF (Inventor)
- COMBINATION THERAPY WITH CD13-TARGETED CHIMERIC PROTEINS OR CHIMERIC PROTEIN COMPLEXES (Inventor)
- FIBROBLAST BINDING AGENTS AND USE THEREOF (Inventor)