Researcher
Tineke Vanderhaeghen
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Adaptive immunology, Bacteriology
- Disciplines (Ghent University):Biophysics, Molecular and cell biology, Laboratory medicine, Microbiology, Systems biology, Plant biology, Medicinal and biomolecular chemistry
Affiliations
- Beyaert Lab (Research group)
Member
From1 Oct 2018 → 31 Dec 2021 - Libert Lab (Research group)
Member
From1 Jan 2017 → Today - Department of Biomedical molecular biology (Department)
Member
From1 Oct 2016 → Today
Publications
1 - 10 of 16
- The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function(2023)
Authors: Tineke Vanderhaeghen, Steven Timmermans, Melanie Eggermont, Deepika Watts, Jolien Vandewalle, Charlotte Wallaeys, Louise Nuyttens, Joyca De Temmerman, Tino Hochepied, Sylviane Dewaele, et al.
- Point mutation I634A in the glucocorticoid receptor causes embryonic lethality by reduced ligand binding(2022)
Authors: Steven Timmermans, Nicolette J.D. Verhoog, Kelly Van Looveren, Sylviane Dewaele, Tino Hochepied, Melanie Eggermont, Barbara Gilbert, Anne Boerema-de Munck, Tineke Vanderhaeghen, Joke Vanden Berghe, et al.
- Reprogramming of glucocorticoid receptor function by hypoxia(2022)
Authors: Tineke Vanderhaeghen, Steven Timmermans, Deepika Watts, Ville Paakinaho, Melanie Eggermont, Jolien Vandewalle, Charlotte Wallaeys, Lise Van Wyngene, Kelly Van Looveren, Louise Nuyttens, et al.
- Hepatic peroxisome proliferator-activated receptor alpha dysfunction in porcine septic shock(2022)
Authors: Jolien Vandewalle, Bruno Garcia, Steven Timmermans, Tineke Vanderhaeghen, Lise Van Wyngene, Melanie Eggermont, Hester Dufoor, Céline Van Dender, Fëllanza Halimi, Siska Croubels, et al.
- Turning a pathogen protein into a therapeutic tool for sepsis(2021)
Authors: Tineke Vanderhaeghen, Charlotte Wallaeys, Claude Libert
- Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis(2021)
Authors: Jolien Vandewalle, Steven Timmermans, Ville Paakinaho, Lies Vancraeynest, Liza Dewyse, Tineke Vanderhaeghen, Charlotte Wallaeys, Lise Van Wyngene, Kelly Van Looveren, Louise Nuyttens, et al.
Pages: 1763 - 1776.e5 - The effect of hypoxia and hypoxia inducible factors on the glucocorticoid receptor function and their role during sepsis(2021)
Authors: Tineke Vanderhaeghen
- Bidirectional crosstalk between hypoxia inducible factors and glucocorticoid signalling in health and disease(2021)
Authors: Tineke Vanderhaeghen, Rudi Beyaert, Claude Libert
- ZBTB32 performs crosstalk with the glucocorticoid receptor and is crucial in glucocorticoid responses to starvation(2021)
Authors: Lise Van Wyngene, Tineke Vanderhaeghen, Steven Timmermans, Katrien Corbeels, Bart Van der Schueren, Jolien Vandewalle, Kelly Van Looveren, Charlotte Wallaeys, Melanie Eggermont, Sylviane Dewaele, et al.
- Taking the STING out of sepsis?(2020)
Authors: Jolien Vandewalle, Tineke Vanderhaeghen, Rudi Beyaert, Claude Libert
Pages: 491 - 493