Researcher
Frederik De Smet
- Disciplines:Macromolecular and materials chemistry, Laboratory medicine, Morphological sciences
Affiliations
- Translational Cell & Tissue Research (Division)
Member
From1 Oct 2016 → Today - Switch Laboratory (VIB-KU Leuven) (Division)
Member
From1 Jan 2011 → 30 Sep 2016 - Centre for Molecular and Vascular Biology (Division)
Member
From15 Nov 2003 → 30 Sep 2005
Projects
21 - 30 of 47
- Advanced image analysis for immunotherapy response prediction in melanomaFrom1 Oct 2020 → 31 Jul 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- Generation of nanobodies against immunomodulating checkpoint receptors in glioblastoma tumor cellsFrom1 Oct 2020 → 30 Sep 2022Funding: BOF - projects
- OrganID: Organ-derived complex 2D/3D cultures in human diseaseFrom1 Oct 2020 → TodayFunding: FWO Strategic Basic Research (SBO)
- Proof of concept: immunotherapy in glioblastoma multiforme.From21 Sep 2020 → TodayFunding: FWO fellowships
- Improving immuno-oncology diagnostics by high-dimensional correlation analysis of histopathology and proteomics data in breast cancer samplesFrom4 Sep 2020 → 22 Feb 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- Combinatorial and personalized oncolytic virotherapy in the battle against glioblastomaFrom29 Aug 2020 → TodayFunding: FWO fellowships
- Integration of complementary, high throughput single-cell omics with spatial resolution.From1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Next-generation pathology by MILAN: multiplex immunohistochemistry and advanced trainable image analysisFrom1 Jan 2020 → 31 Dec 2021Funding: IOF - technology validation in lab
- Screening of Hyp-PDT induced ICD-sensitive GBM Immunophenotype and Exploration of Synergetic Effect of Sonodynamic Therapy in GBM ImmunotherapyFrom2 Dec 2019 → 2 Dec 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Characterization and analysis of in vivo intracranial models for glioblastomaFrom1 Dec 2019 → 31 Mar 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 67
- Recent advancements in tumour microenvironment landscaping for target selection and response prediction in immune checkpoint therapies achieved through spatial protein multiplexing analysis.(2024)
Authors: Madhavi Dipak Andhari, Frederik De Smet, Francesca Bosisio
Pages: 207 - 237 - Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma(2023)
Authors: Lise Finotto, Frederik De Smet, Ilse Geudens
- Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma(2023)
Authors: Lise Finotto, Basiel Cole, Maxime Vanmechelen, Bram Boeckx, Diether Lambrechts, Ludo Van Den Bosch, Steven De Vleeschouwer, Frederik De Smet
- ESTABLISHING A CLINICALLY RELEVANT MOUSE MODEL OF MESENCHYMAL GLIOBLASTOMA FOR STUDYING TME TARGETING TREATMENTS.(2023)
Authors: Ingrid Arijs, Diether Lambrechts, Frederik De Smet
- Extended heterogeneity mapping of pediatric brain tumors(2023)
Authors: Julie Messiaen, Frederik De Smet, Sandra Jacobs
- The tumor micro-environment in pediatric glioma: friend or foe?(2023)
Authors: Sandra Jacobs, Frederik De Smet
- Transcriptional and spatial profiling of the kidney allograft unravels a central role for FcyRIII plus innate immune cells in rejection(2023)
Authors: Yannick Van Herck, Frederik De Smet, Katrien De Vusser, Amelie Franken, Dirk Kuypers, Diether Lambrechts, Elisabet Van Loon, Thibaut Vaulet, Francesca Bosisio, Maarten Naesens
- ALK Amplification and Rearrangements Are Recurrent Targetable Events in Congenital and Adult Glioblastoma(2023)
Authors: Veerle Haemels, Frederik De Smet
Pages: 2651 - 2667 - Spatially resolved intracellular delivery of molecules at single cell level on a microelectrode array(2023)
Authors: Bastien Duckert, Liesbet Lagae, Rik Gijsbers, Frederik De Smet
Number of pages: 124 - Functional Precision Oncology: Next-generation treatment rationale for glioblastoma Mapping the drug response heterogeneity using single cell protein analysis(2023)
Authors: Dena Panovska, Frederik De Smet
Patents
1 - 5 of 5
- Means and methods for generating improved proteins (Inventor)
- Means and methods for generating improved proteins (Inventor)
- Extracellular allosteric inhibitor binding domain from a tyrosine kinase receptor (Inventor)
- Methods for screening inhibitors of tumor associated protein aggregation (Inventor)
- Methods for screening inhibitors of tumour associated protein aggregation. (Inventor)