Researcher
Frederik De Smet
- Disciplines:Macromolecular and materials chemistry, Laboratory medicine, Morphological sciences
Affiliations
- Translational Cell & Tissue Research (Division)
Member
From1 Oct 2016 → Today - Switch Laboratory (VIB-KU Leuven) (Division)
Member
From1 Jan 2011 → 30 Sep 2016 - Centre for Molecular and Vascular Biology (Division)
Member
From15 Nov 2003 → 30 Sep 2005
Projects
11 - 20 of 47
- Single-cell and spatial multi-omics for biomedicineFrom1 Oct 2022 → TodayFunding: IOF - mandates
- Training the next-generation of European GLIOblastoma (translational) researchers, to RESOLVE precision targeting of the brain tumour microenvironmentFrom1 Sep 2022 → TodayFunding: HORIZON.1.2 - Marie Skłodowska-Curie-actions (MSCA)
- Single-objective light sheet instrument for fast and highthroughput imaging of 3D tissueFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Next-generation, multi-technology immune-monitoring and easy-access spectral flow cytometryFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Tool development for multi-omic data integrationFrom1 Mar 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Mapping single-cell drug responses in GlioblastomaFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Innovate sensors and imaging for organoid-based disease models.From15 Nov 2021 → 29 Sep 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- Radiation-induced proneural-to-mesenchymal transition in glioblastoma: how does it work and how can it be prevented?From1 Oct 2021 → TodayFunding: FWO fellowships, SCK (Study Centre Nuclear Energy)
- Evaluation of the therapeutic value of asparaginase for the treatment of glioblastomaFrom30 Mar 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Next-generation multiplex pathology: enabling precision medicine by improving cancer diagnostics and biomarker identification.From1 Feb 2021 → 31 Jan 2024Funding: Foundations, funds and other with scientific goal
Publications
1 - 10 of 67
- Recent advancements in tumour microenvironment landscaping for target selection and response prediction in immune checkpoint therapies achieved through spatial protein multiplexing analysis.(2024)
Authors: Madhavi Dipak Andhari, Frederik De Smet, Francesca Bosisio
Pages: 207 - 237 - Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma(2023)
Authors: Lise Finotto, Frederik De Smet, Ilse Geudens
- Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma(2023)
Authors: Lise Finotto, Basiel Cole, Maxime Vanmechelen, Bram Boeckx, Diether Lambrechts, Ludo Van Den Bosch, Steven De Vleeschouwer, Frederik De Smet
- ESTABLISHING A CLINICALLY RELEVANT MOUSE MODEL OF MESENCHYMAL GLIOBLASTOMA FOR STUDYING TME TARGETING TREATMENTS.(2023)
Authors: Ingrid Arijs, Diether Lambrechts, Frederik De Smet
- Extended heterogeneity mapping of pediatric brain tumors(2023)
Authors: Julie Messiaen, Frederik De Smet, Sandra Jacobs
- The tumor micro-environment in pediatric glioma: friend or foe?(2023)
Authors: Sandra Jacobs, Frederik De Smet
- Transcriptional and spatial profiling of the kidney allograft unravels a central role for FcyRIII plus innate immune cells in rejection(2023)
Authors: Yannick Van Herck, Frederik De Smet, Katrien De Vusser, Amelie Franken, Dirk Kuypers, Diether Lambrechts, Elisabet Van Loon, Thibaut Vaulet, Francesca Bosisio, Maarten Naesens
- ALK Amplification and Rearrangements Are Recurrent Targetable Events in Congenital and Adult Glioblastoma(2023)
Authors: Veerle Haemels, Frederik De Smet
Pages: 2651 - 2667 - Spatially resolved intracellular delivery of molecules at single cell level on a microelectrode array(2023)
Authors: Bastien Duckert, Liesbet Lagae, Rik Gijsbers, Frederik De Smet
Number of pages: 124 - Functional Precision Oncology: Next-generation treatment rationale for glioblastoma Mapping the drug response heterogeneity using single cell protein analysis(2023)
Authors: Dena Panovska, Frederik De Smet
Patents
1 - 5 of 5
- Means and methods for generating improved proteins (Inventor)
- Means and methods for generating improved proteins (Inventor)
- Extracellular allosteric inhibitor binding domain from a tyrosine kinase receptor (Inventor)
- Methods for screening inhibitors of tumor associated protein aggregation (Inventor)
- Methods for screening inhibitors of tumour associated protein aggregation. (Inventor)