Researcher
Chris Marine
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Morphological sciences, Oncology
Affiliations
- Laboratory for Molecular Cancer Biology (VIB-KU Leuven) (Division)
Responsible
From1 Jan 2017 → Today - VIB-KU Leuven Center for Cancer Biology (Research Center)
Responsible
From1 Jan 2017 → Today - Marine Lab (Research group)
Responsible
From1 Jan 2017 → Today - Laboratory for Molecular Cancer Biology (VIB-KU Leuven) (Division)
Member
From1 Oct 2013 → Today - Department of Human Genetics (Department)
Member
From1 Oct 2009 → 31 Dec 2016
Projects
1 - 10 of 62
- Understanding and targeting melanoma mesenchymal-like cells to improve response to immunotherapyFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Spatio-temporal dissection of inter-cellular melanoma communication networks that contribute to resistance to immunotherapy.From1 Oct 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Empowering precision medicine in melanoma: Exploring the potential of an implantable microdevice for large-scale drug screening in vivoFrom12 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Microfluidic tools to study single-cell responses and cell-cell communication in cancer applicationsFrom1 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Identification of universal biomarkers of metastatic melanoma in CTCsFrom30 May 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Detection and prevention of early metastatic dissemination of melanomaFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Dissecting the heterotypic cell communication networks at the perivascular niche to detect andintercept the early metastatic processFrom1 Jan 2023 → TodayFunding: BOF - iBOF
- Dissecting the cellular and molecular interaction networks that promote melanoma stemness at the perivascular niche.From1 Oct 2022 → TodayFunding: FWO senior postdoctoral fellowship
- Circulating tumor cells as a target of anti-metastatic treatment in melanoma.From1 Sep 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Molecular Cartography (Resolve Biosciences) , a single-molecule fluorescent in situ hybridization (smFISH) platform.From25 Aug 2022 → TodayFunding: Other federal scientific institutions
Publications
21 - 30 of 158
- Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop(2022)
Authors: Yichao Hua, Gerlanda Vella, Ann Smeets, David Nittner, Francesca Bosisio, Beppe Floris, Diether Lambrechts, Chris Marine, Susan Schlenner, Gabriele Bergers
Pages: 1600 - + - Comparative single-cell RNA-sequencing profiling of BMP4-treated primary glioma cultures reveals therapeutic markers(2022)
Authors: Panagiotis Karras, Chris Marine, Danny Huylebroeck
Pages: 2133 - 2145 - p53 Reactivation by PRIMA-1Met (APR-246) sensitises V600E/KBRAF melanoma to vemurafenib (vol 55, pg 98, 2016(2022)
Authors: Chris Marine
Pages: 336 - 338 - Corrigendum to 'p53 Reactivation by PRIMA-1Met (APR-246) sensitises V600E/KBRAF melanoma to vemurafenib'[Eur J of Cancer 55 (2016) 98-110].(2022)
Authors: Chris Marine
Pages: 336 - 338 - A cellular hierarchy in melanoma uncouples growth and metastasis (vol 610, pg 190, 2022)(2022)
Authors: Panagiotis Karras, Joanna Poźniak, Nina Van Raemdonck, Ewout Landeloos, Yannick Van Herck, Michael Dewaele, Yichao Hua, Gabriele Bergers, Francesca Bosisio, Joost van den Oord, et al.
Pages: E4 - E4 - A cellular hierarchy in melanoma uncouples growth and metastasis(2022)
Authors: Panagiotis Karras, Ada Nowosad, Nina Van Raemdonck, Ewout Landeloos, Yannick Van Herck, Dennis Pedri, Michael Dewaele, Yichao Hua, Gabriele Bergers, Francesca Bosisio, et al.
Pages: 190 - + - Mapping the Immune Landscape in Metastatic Melanoma Reveals Localized Cell-Cell Interactions That Predict Immunotherapy Response(2022)
Authors: Yannick Van Herck, Veerle Boecxstaens, Chris Marine, Joost van den Oord, Frederik De Smet, Oliver Bechter, Francesca Bosisio
Pages: 3275 - 3290 - Treatment for giant congenital nevi moves a step closer(2022)
Authors: Chris Marine
Pages: 799 - 800 - PHGDH heterogeneity potentiates cancer cell dissemination and metastasis (vol 605. pg 747, 2022)(2022)
Authors: Margherita Demicco, Anke Vandekeere, Juan Fernandez Garcia, Carla Riera Domingo, David Nittner, Francesca Rizzollo, Panagiotis Karras, dorien Broekaert, Sofie Demeyer, Ayse Bassez, et al.
Pages: E8 - E8 - A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression(2022)
Authors: Panagiotis Karras, Chris Marine
Pages: 940 - +
Patents
1 - 10 of 10
- Inhibition of neat1 for treatment of solid tumors (Inventor)
- Targeting minimal residual disease in cancer with cd36 antagonists (Inventor)
- Direct and selective inhibition of mdm4 for treatment of cancer (Inventor)
- Tumor minimal residual disease stratification (Inventor)
- Targeting minimal residual disease in cancer with rxr antagonists (Inventor)
- Targeting minimal residual disease in cancer with cd36 antagonists (Inventor)
- Targeting minimal residual disease in cancer with rxr antagonists (Inventor)
- Tumor minimal residual disease stratification (Inventor)
- Inhibition of neat1 for treatment of solid tumors (Inventor)
- Inhibition of a lncrna for treatment of melanoma (Inventor)