Researcher
Bart De Spiegeleer
- Keywords:Pharmaceuticals
- Disciplines:In vitro testing, Non-clinical studies, Molecular medicine, Separation techniques, Spectrometry, Drug regulation, Medical systems biology not elsewhere classified
Affiliations
- Department of Pharmaceutical analysis (Department)
Member
From1 Oct 2003 → Today
Projects
1 - 10 of 21
- The role of the quorum sensing peptide PapRIV in regulating microglia.From1 Oct 2021 → TodayFunding: BOF - projects
- Development of a live biotherapeutic medicine against colorectal cancer metastasis.From1 Jan 2021 → 31 Dec 2023Funding: IOF - technology validation in lab
- The in vivo role of quorum sensing peptides in metastatic colorectal cancer.From1 Nov 2020 → 28 Feb 2021Funding: FWO Strategic Basic Research Grant
- The development of 68-gallium-NOTA-somatropin, a targeted radiopharmaceutical for the diagnosis of growth hormone receptor-positive cancers.From1 Nov 2020 → TodayFunding: FWO Strategic Basic Research Grant
- Development of artemisinin-derived medicines to improve stability and pharmacokinetic propertiesFrom1 Oct 2020 → TodayFunding: BOF - doctoral mandates
- Controlled delivery of connexin43 mimetic peptide by nanocontainers for therapy of systemic inflammationFrom1 Oct 2018 → 31 Jul 2023Funding: BOF - Doctoral projects
- MSsmall: mass spectrometry for small organic moleculesFrom1 Feb 2017 → 30 Nov 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- 68Gallium- and 177Lutetium/NOTA-somatropin for imaging and treatment of GH-R expressing melanomaFrom1 Jan 2017 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- The presence of quorum sensing peptides in clinical samples: their biological role in oncology.From1 Jan 2017 → 31 Dec 2020Funding: FWO Strategic Basic Research Grant
- Development of in-vivo relevant dissolution systems for selected neglected-diseases medicinesFrom1 Aug 2014 → 30 Sep 2020Funding: BOF - Doctoral projects
Publications
1 - 10 of 304
- Streptococcal quorum sensing peptide CSP-7 contributes to muscle inflammation and wasting(2024)
Authors: Anton De Spiegeleer, Amélie Descamps, Evelien Wynendaele, Liesbeth Crombez, Marta Planas, Lidia Feliu, Daniel Knappe, Vincent Mouly, Anne Bigot, Rafael Bielza, et al.
- Characterizing non-covalent protein complexes using asymmetrical flow field-flow fractionation on-line coupled to native mass spectrometry(2023)
Authors: Iro Konstantina Ventouri, Wayne Chang, Florian Meier, Roland Drexel, Govert W. Somsen, Peter J. Schoenmakers, Bart De Spiegeleer, Rob Haselberg, Alina Astefanei
Pages: 7487 - 7494 - Peptidomics : LC-MS operational parameters do matter(2023)
Authors: Amélie Descamps, Kevin Van der borght, Anton De Spiegeleer, Evelien Wynendaele, Bart De Spiegeleer
- Potential role of statins in treatment of acute sarcopenia(2023)
Authors: Anton De Spiegeleer, Liesbeth Crombez, Amélie Descamps, Roland Rössler, Reto W. Kressig, Bruno Lapauw, Evelien Wynendaele, Dirk Elewaut, Bart De Spiegeleer, Nele Van Den Noortgate
- Evaluation of greenness and analytical performances of separative methods for chiral separation of novel lactam-based P2RX7-antagonists(2023)
Authors: Lorenzo Avigo, Christophe Furman, Alina Ghinet, Teodora Sandu, Evelien Wynendaele, Bartosz Wielgomas, Bart De Spiegeleer, Emmanuelle Lipka
Pages: 218 - 233 - Emerging pharmaceutical therapies of Ascidian-derived natural products and derivatives(2023)
Authors: Kris Cooreman, Bart De Spiegeleer, Christof Van Poucke, David Vanavermaete, Daan Delbare, Evelien Wynendaele, Bavo De Witte
- The quorum sensing peptide EntF* promotes colorectal cancer metastasis in mice : a new factor in the host-microbiome interaction(2022)
Authors: Evelien Wynendaele, Nathan Debunne, Anton De Spiegeleer, Frederick Verbeke, Liesa Tack, Sophie Van Welden, Evy Goossens, Daniel Knappe, Ralf Hoffmann, Debby Laukens, et al.
- Quality-by-design principles applied to the establishment of a pharmaceutical quality control laboratory in a resource-limited setting : the lab water(2022)
Authors: Sultan Suleman, Sileshi Belew Yohannes, Dereje Kebebe, Markos Duguma, Henok Teshome, Gemmechu Hasen, Evelien Wynendaele, Luc Duchateau, Bart De Spiegeleer
- The bacterial quorum sensing peptide iAM373 is a novel inducer of sarcopenia(2022)
Authors: Anton De Spiegeleer, Evelien Wynendaele, Amélie Descamps, Nathan Debunne, Bart Braeckman, Julie Coudenys, Liesbeth Crombez, Frederick Verbeke, Rekin's Janky, Evy Goossens, et al.
- Liquid chromatography-mass spectrometry (LC-MS) analysis of bioactive peptides(2022)Series: Food analysis & properties
Authors: Evelien Wynendaele, Kevin Van der borght, Nathan Debunne, Bart De Spiegeleer, Leo M.L. Nollet, Semih Ötleş
Pages: 301 - 320
Patents
1 - 3 of 3