VIB Screening Core Flanders Institute for Biotechnology
Responsible
Development of miniaturized test systems and assays to accelerate the discovery of biologically active substances.
Find expertise
Wim Martinet University of Antwerp
Freke Mertens University of Antwerp
Pieter Van Der Veken University of Antwerp
Medicinal Chemistry (UAMC) University of Antwerp
Responsible
The research topics in the Department of Medicinal Chemistry deal with the development of new medicines and focus mainly on following topics: 1. The investigation of enzymes as target for the design of biologically active compounds. Making use of the substrate selectivity of the enzyme, inhibitors are developed. Various medicinal chemical strategies and 'in silico' chemistry are used. These inhibitors are synthetized and chemically ...
Physiopharmacology (PHYSPHAR) University of Antwerp
Responsible
The research of the Laboratory of Physiopharmacology is focused on the cardiovascular system. A first line of research involves the morphological and haemodynamic changes that occur during the development and rupture of atherosclerotic plaques. Various experimental models have been established in rabbits and in genetically modified mice. Recently, we developed for the first time a model of atherosclerosclerotic plaque rupture in mice with ...