Projects
Synthesis of diamino acid derivatives with a cyclopropane or aziridine skeleton and their application in the synthesis of potential physiologically active alpha, gamma-dimainobutyric acid derivatives Ghent University
The synthesis of constrained x, B- or x, Y-diamino acid derivatives as building blocks for new substituted 2,4-diaminobutyric acid derivatives is of great importance in medicinal and agricultural chemistry. This research concerns the development of stereoselective syntheses and biochemical evaluation of new derivatives of 1,2-diaminocyclopropane-1-carboxylic acid, 2-amino-2-aziridin-2-ylacetic acid and 2-amino-3-aziridin-2-ylpropionic acid ...
Physical anthropological study of selected skeletons excavated at the site 'Nieuwpoort - OLV church Vrije Universiteit Brussel
During the excavations 196 individuals could be ...
Funtionalised Azabicycloalkanes as conformational restricted Skeletons for structural Analogues of physiological active compounds Ghent University
The cyanide induced dynamic intramolecular cyclization will be further developed for the synthesis of new azabicyclic skeletons which are important in agrochemistry and pharmaceutical industry. During this study, the attention will be focussed on the synthesis of new 2,4-methanoproline analogues (anti-feedant) as well as tricyclic methanoproline analogues and the syntesis of epibatidine analogues (analgesic activity).
MEMOR. A database and ethical framework for human skeletons from archaeological contexts in Flanders Ghent University
Linking metabolic alterations to skeletal cell dysfunction during bone pathology KU Leuven
To maintain its structure and function, the skeleton is continuously remodeled by bone-forming osteoblasts and bone-resorbing osteoclasts. Not surprisingly, disturbed cellular activity is associated with several types of skeletal disease. The most common metabolic bone disease is osteoporosis, which is characterized by low bone mass, skeletal frailty and the accumulation of bone marrow adipocytes. Recent studies have shown that different ...
BioMedAqu: Aquaculture meets Biomedicine: Innovation in Skeletal Health research Ghent University
Skeletal anomalies in farmed fish are a continuous problem for global aquaculture, affecting fish welfare, performance, and product quality. Aquaculture research has made considerable progress in reducing the incidence of deformities, but new species, intensified production, the damned for sterile fish, delicate early life stages and new fish feed ingredients are a continuous challenge. The use of zebrafish (Danio rerio) and medaka (Oryzias ...
Linking metabolic alterations to skeletal cell dysfunction during bone pathology KU Leuven
BioMedAqu: Aquaculture meets Biomedicine: Innovation in Skeletal Health research Ghent University
Skeletal anomalies in farmed fish are a continuous problem for global aquaculture, affecting fish welfare, performance, and product quality. Aquaculture research has made considerable progress in reducing the incidence of deformities, but new species, intensified production, the damned for sterile fish, delicate early life stages and new fish feed ingredients are a continuous challenge. The use of zebrafish (Danio rerio) and medaka (Oryzias ...