DNA-functionalized fibrous hydrogels to quantify cell-matrix interactions KU Leuven
Cells physically interact with the extracellular matrix (ECM) through cellular forces. These forces are involved in matrix remodeling, cell‑cell mechanical communication, and tissue mechanics, further guiding cell migration and development. Several reports indicate that cells can physically remodel ECM through fiber alignment and densification, creating a mechanically specific micro-niche to suit their needs. At the same time, the forces ...