The effects of advanced paternal age on clinical outcomes in assisted reproductive technology KU Leuven
Female age is well known to interfere with reproductive health. There are currently no guidelines or recommendations for future fathers. However, animal models and a number of findings in humans have shown that fertility can be affected by age of the male partner. In mice, older males produce less offspring and in-vitro experiments show adverse effects on blastocyst development and pregnancy success if males are older than 12 months. A ...