Development of a toolbox for temporal monitoring of pediatric cancers using liquid biopsy samples Ghent University
Despite intensive treatment regimens, around 20% of children confronted with cancer will succumb to their disease. Low survival rates of high-risk neuroblastoma and Wilms tumor patients can often be attributed to the development of therapy resistance, resulting in tumor recurrence and refractory disease. In the case of high-risk neuroblastoma and Wilms tumors, both genetic heterogeneity and epigenetic plasticity have been shown to be involved ...