Projects

1 - 10 of 42 results

Search term:

Combatting Bacterial Resistance in Europe – Carbapenem Resistance (COMBACTE‐CARE). University of Antwerp

Herman Goossens
Laboratory of Medical Microbiology (LMM), Vaccine & Infectious Disease Institute (VAXINFECTIO)
COMBACTE‐CARE (aligned with the COMBACTE infrastructure) will (1) increase the efficiency of antibiotic R&D through analysing observational clinical and microbiological data sets and making recommendations for the development of novel antibiotic agents for MDR GNB; will (2) provide new knowledge on the clinical management and outcomes of patients (neonates/children and adults)with serious hospitalised infections and will validate this ...

Development and application of statistical methodology for analysis of the phenomenon of multi-drug resistance in the EU: demonstration of analytical approaches using antimicrobial resistance isolate-based data. Hasselt University

Marc AERTS
Centre for Statistics
In accordance with Decision 2013/652/EC, harmonisation of monitoring of antimicrobial resistance (AMR) in animals and food reporting will be further enhanced in the EU and reporting of AMR data at isolate level by MSs to EFSA will become mandatory from calendar year 2015 and onwards (2014 data and onwards). Based on AMR isolate-based data reported on a voluntary basis, the 2012 EU Summary Report on AMR summarises important information on ...

Enhanced Networking on Antimicrobial Resistance Surveillance with Next Generation Sequencing (AmReSu). University of Antwerp

Surbhi Malhotra
Laboratory of Medical Microbiology (LMM)
Antimicrobial resistance (AMR) is on the rise, resulting in 700 000 deaths worldwide every year. In Croatia and Hungary, AMR is responsible for the rapid increase in morbidity and mortality rates. The EU-funded AmReSu project will strengthen the innovation capacity in AMR surveillance in both countries, focussing on whole genome sequencing in correlation with next-generation sequencing techniques. It will also establish an "AMR surveillance ...

The value of diagnostics to combat antimicrobial resistance by optimising antibiotic use (VALUE-Dx). University of Antwerp

Herman Goossens
Laboratory of Medical Microbiology (LMM)
Antimicrobial resistance (AMR) is of great public health concern, causing numerous losses of lives worldwide and threatening to reverse many of the considerable strides modern medicine has made over the last century. There is a need to stratify antibiotic and alternative treatments in terms of the actual benefit for the patient, improving patient outcome and limit the impact on AMR. High quality, effective and appropriate diagnostic tests to ...

Disseminating Innovative Solutions for Antibiotic Resistance Management - DISARM Ghent University

Jeroen Dewulf
Department of Internal Medicine, Reproduction and Population Medicine

The DISARM thematic network (Disseminating Innovative Solutions for Antibiotic Resistance Management) is focused on disseminating best practices from innovative farms and research on how to reduce antibiotic resistance in livestock farming. Antibiotic resistance management is not only important to farming, it can also lead to reduced effectiveness of antibiotics in treating humans. Tackling antibiotic resistance is a major strategic challenge ...

Combatting Antimicrobial Resistance Training Network Ghent University

Patrick Butaye
Department of Pathobiology, Pharmacology and Zoological Medicine

The discovery of antibiotics in the 1950s saved millions of lives from once-deadly diseases such as tuberculosis, plague, pneumoniae and even simple wound infections. Moreover, antibiotics opened new possibilities for complex medical interventions such as organ transplants or cancer treatment, that were previously practically impossible due to risk of life-threatening infections. However, the over- and misuse of antibiotics in humans, ...

Combatting Bacterial Resistance in Europe - Clostridium Difficile Infections (Combacte - CDI). University of Antwerp

Herman Goossens
Laboratory of Medical Microbiology (LMM), Vaccine & Infectious Disease Institute (VAXINFECTIO)
Clostridium difficile infection (CDI) is one of the most prevalent healthcare associated infections, affecting both hospitalized patients and individuals in the community; notably, there is an increasing realization that cases also occur in subjects not recently exposed to healthcare interventions, including antibiotics. CDI poses an extensive burden of morbidity, mortality and healthcare resource utilization, and so requires effective ...

To the roots of induced systemic resistance in the Arabidopsis-Trichoderma-Fusarium tripartite interaction KU Leuven

Bruno Cammue
Centre of Microbial and Plant Genetics

Biological control organisms (BCOs) can form an important component of more sustainable agriculture. Trichoderma spp. are soil fungi with great potential in this respect. They can trigger induced systemic resistance (ISR) in the plant, leading to a more rapid and robust systemic activation of defense when the plant is subsequently challenged by a pathogen. However, genome-wide investigations of the tripartite plant-Trichoderma-pathogen ...