Publications
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Secure and efficient application monitoring and replication Ghent University
Thoracic dimples and dysmorphic features associated with a partial duplication and triplication of chromosome 12q24 University of Antwerp
Implication and Axiomatization of Functional Constraints on Patterns with an Application to the RDF Data Model Hasselt University
Akhtar et al. introduced equality-generating constraints and functional constraints as an initial step towards dependency-like integrity constraints for RDF data [1]. Here, we focus on functional constraints. The usefulness of functional constraints is not limited to the RDF data model. Therefore, we study the functional constraints in the more general setting of relations with arbitrary arity. We show that a chase algorithm for functional ...
Participation aspects in the realisation of the Nete River basin management plan: methodology and application University of Antwerp
Quinolinecarboxamides Inhibit the Replication of the Bovine Viral Diarrhea Virus by Targeting a Hot Spot for the Inhibition of Pestivirus Replication in the RNA-Dependent RNA Polymerase KU Leuven
The bovine viral diarrhea virus (BVDV), a pestivirus from the family of Flaviviridae is ubiquitous and causes a range of clinical manifestations in livestock, mainly cattle. Two quinolinecarboxamide analogues were identified in a CPE-based screening effort, as selective inhibitors of the in vitro bovine viral diarrhea virus (BVDV) replication, i.e., TO505-6180/CSFCI (average EC50 = 0.07 µM, SD = 0.02 µM, CC50 > 100 µM) and TO502-2403/CSFCII ...
Theory Building Through Replication Response to Commentaries on the "Many Labs" Replication Project KU Leuven
Reverse replication of circular micro grating structures with soft lithography Ghent University
In this work, the reverse replication of circular micro grating structures on glass substrates is implemented using an ultra-violet curable resin and a polydimethylsiloxane (PDMS) mold which has the same structure as the original circular grating master. Two different techniques ("double PDMS replication" and "polymer-PDMS replication") are employed to fabricate those reversed circular micro grating structures. Surface profiling measurements ...
Novel strategies to inhibit enterovirus replication KU Leuven
Picornavirussen vormen een grote, wijdverspreide virusfamilie die ingedeeld wordt in negen genera. In de humane geneeskunde zijn entero- en rhinovirussen de twee meest relevante genera. Rhinovirussen zijn de belangrijkste oorzaak van verkoudheden en hoewel meestal niet levensbedreigend, hebben ze een enorme socio-economische impact (verloren school- en werkdagen). Daarenboven wijzen meer en meer studies erop dat rhinovirussen betrokken zijn bij ...
The role of LEDGF/p75 in HIV replication Analysis of knockdown and knockout cell lines and translational implications KU Leuven
HIV, the causative agent of AIDS affects more than 34 million people worldwide. Controlling the HIV pandemic and ultimately curing HIV remains one of the major challenges in medicine. Although antiretroviral drugs have markedly changed the outcome of HIV infected patients, converting a deadly disease into a chronic infection, they are not without important problems and drawbacks. Even with the most effective antiretroviral drug combinations, ...