Projects
Relevance of beta cell serotonin production during pregnancy. KU Leuven
Evaluation of chemotherapy-associated fetal damage in cancer in pregnancy KU Leuven
Though rare, cancer in pregnancy is becoming more frequent due to the trend to postpone pregnancies until a later age. In large-scale clinical studies, we showed that chemotherapy given during pregnancy has no adverse effect on the short-term health of the infants. Yet, these children appear to be more often small for their gestational age, have a lower verbal IQ and increased chance of wearing glasses at the age of 6. Long-term health ...
Pregnancy and Cancer: the INCIP Project KU Leuven
Cancer diagnosis and treatment in young pregnant women challenges oncological decision-making. The International Network on Cancer, Infertility and Pregnancy (INCIP) aims to contribute to the creation of clinical recommendations based on global multicentric research. This doctoral project will be a continuation of the ongoing collaborative analysis of the INCIP database with a focus on maintaining and updating the international registry, as ...
PREMOM II: pregnancy remote monitoring of women at risk for gestational hypertensive disorders. KU Leuven
Our goal is to implement telemonitoring (TM) in the prenatal care for pregnant women with a raised risk of gestational hypertensive disorders (GHA) throughout Flanders. When this technology is applied in all Flemish MIC centers, almost every pregnant woman will have access to this prenatal program that will improve the outcomes of herself and their neonate.
PRENOM II : Pregnancy remote monitoring of women at risk for gestational hypertensive disorders Hasselt University
Why do mouse beta cells produce serotonin during pregnancy? KU Leuven
Pancreatic beta cells are unique in that only they can release insulin, a crucial hormone for blood glucose homeostasis. Furthermore, the rate of insulin release is tightly regulated to the metabolic need. Failure of this regulation, either by destruction of beta cells or insufficient insulin release, causes diabetes. During pregnancy beta cells undergo several changes to adapt to the higher insulin demands of the mother, which support the ...
PRegnancy Exposome influence on early-life COgnition via CholEsterol metabolism at birth (PRECOCE) Hasselt University
Extracellular vesicles as non-invasive biomarkers for assessing the competence of human embryos to implant and establish a clinical pregnancy Ghent University
Infertility is a major problem in the human population. Despite significant advances in assisted reproductive technologies, such as in vitro fertilization (IVF), a pregnancy can only be established in 30% of IVF-cycles, as the quality of the embryo plays a major role in initiating the pregnancy. Recently our group has demonstrated the release of microRNAs and extracellular vesicles (EVs) by bovine embryos into the culture medium. We also ...
Assessing the risk of SARS-CoV-2 infection for pregnancy and as possible cause of birth defects Vrije Universiteit Brussel
over the globe. Mortality rate is highest among the elderly while
people at reproductive age usually experience mild or no symptoms.
At current, data on SARS-CoV-2 infection during pregnancy are
limited. Whereas infection during late trimester pregnancy seems to
occur without adverse events, a recent study reported maternal and
neonatal ...