Towards PREcision MEdicine for Osteoarthritis: added value of cognitive behavioural therapy for insomnia (the PREMEO trial) KU Leuven
Knee osteoarthritis (KOA) is the leading and fastest increasing cause of disability in older adults. It is a serious health issue related with a high health care utilisation. The first-line KOA management is nonsurgical care, with education and exercise therapy as key elements. Nevertheless, treatment effects of exercise therapy and behavioral pain management on improvements in pain, function and quality of life are small to moderate at ...