Publications
Usefulness of medicine screening tools in the frame of pharmaceutical post-marketing surveillance Institute of Tropical Medicine
The negative consequences of Substandard and falsified (SF) medicines are widely documented nowadays and there is still an urgent need to find them in more efficient ways. Several screening tools have been developed for this purpose recently. In this study, three screening tools were used on 292 samples of ciprofloxacin and metronidazole collected in Cameroon. Each sample was then analyzed by HPLC and disintegration tests. Seven additional ...
in vitro antimicrobial sensitivity of Neisseria gonorrhoeae from Rwanda Institute of Tropical Medicine
Analysis of new persistence determinants in Pseudomonas aeruginosa identified by high-throughput screening KU Leuven
Population-based resistance of Mycobacterium tuberculosis isolates to pyrazinamide and fluoroquinolones: results from a multicountry surveillance project Institute of Tropical Medicine University of Antwerp
Background Pyrazinamide and fluoroquinolones are essential antituberculosis drugs in new rifampicin-sparing regimens. However, little information about the extent of resistance to these drugs at the population level is available.
Methods In a molecular epidemiology analysis, we used population-based surveys from Azerbaijan, Bangladesh, Belarus, Pakistan, and South Africa to investigate resistance to pyrazinamide and fluoroquinolones ...
Correlation of different phenotypic drug susceptibility testing methods for four fluoroquinolones in Mycobacterium tuberculosis Institute of Tropical Medicine University of Antwerp
BACKGROUND: Molecular resistance testing fails to explain all fluoroquinolone resistance, with a continued need for a suitable rapid phenotypic drug susceptibility testing method.
OBJECTIVE: To evaluate the optimal method for phenotypic fluoroquinolone susceptibility testing.
METHODS: Using Löwenstein-Jensen medium, Middlebrook 7H11 agar, BACTEC-MGIT 960 and the resazurin microtitre plate assay, we determined susceptibility to ...