Projects
Novel macrophage and myeloid dendritic cell markers for in vivo imaging and therapy of inflammatory diseases; Inflammation tracking "Inflammatrack" Ghent University
This project will explore (i) the possibility of targeting inflammatory MCs on the basis of specific MC markers and (ii) potential applications of this MC targeting, namely inflammation tracking and therapy of inflammatory diseases. As a consequence of the broad applicability of the anticipated deliverables in the field of inflammation, in fact reflecting the generic nature of the project, different Flemish companies have expressed a direct ...
Novel macrophage and myeloid dendritic cell markers for in vivo imaging and therapy of inflammatory diseases; inflammation trackin "inflammatrack". Vrije Universiteit Brussel
IWT grant: Macrophages as mediators of protectieve auto-immunity. Hasselt University
Disturbed lipophagy skews foamy macrophages to a disease-promotiong phenotype in progressive MS. Hasselt University
Disturbed lipid processing skews foamy macrophages to a disease-promoting phenotype in MS Hasselt University
Reprogramming macrophage fatty acid metabolism to induce repair in multiple sclerosis Hasselt University
Fatty acid metabolism in control of the phenotype in phagocytes in MS lesions Hasselt University
Investigation of axonal transport deficits in Charcot-Marie-Tooth disease type 1A and modification through selective inhibition of histone deacetylase 6 KU Leuven
Charcot-Marie-Tooth disease (CMT) is the most common inherited neurological disorder of the peripheral nervous system (PNS). Patients suffer from mild-to-severe muscle loss at the most distal regions of their body in a ‘stock-glove’ distribution. Duplications in the gene coding for peripheral myelin protein 22 (PMP22) causes the most common form of CMT, CMT type 1A (CMT1A). PMP22 is an essential protein for the initiation and maintenance of ...