Projects
Characterization of new mouse models for frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS). University of Antwerp
Isolation and characterisation of genes affecting low temperature growth in Serratia plymuthica RVH1 KU Leuven
Refrigerated foods are one of the most rapidly growing segments in the food industry. Refrigerated storage is necessary because these foods are perishable and can support growth of microorganisms that can cause spoilage or foodborne disease. Psychrotrophy, i.e. the ability to grow at temperatures below 4 °C, is widespread among bacteria of diverse phylogenetic lineages, but often varies at the genus, species or even strain level. The ...
Development of a diagnostic method for thermo-elastic characterization of coatings using laser-ultrasonics. KU Leuven
Molecular epidemiology of human cytomegalovirus. KU Leuven
Human cytomegalovirus (HCMV) is a ubiquitous virus that infects the majority of the worldwide population through contact of bodily secretions. Like other herpesviruses, HCMV cannot be cleared and remains latent for the lifetime of its host, providing a source of persistent or sporadic virus secretion and resulting transmission. While the virus can occasionally cause febrile illness or infectious mononucleosis in immunocompetent adults and ...
Genetic diversity of rotaviruses and co-segregation of rotavirus gene segments in reassortants. KU Leuven
Investigation of the molecular basis of the Ehlers-Danlos Syndrome, a genetic model for the study of joint hypermobility Ghent University
Joint hypermobility is a prominent feature of diverse connective tissue diseases a.o. the Ehlers-Danlos syndrome. Little is known about the genetic basis of joint hypermobility and genetic heterogeneity is suggested. In this project a recently identified candidate locus for the hypermobile subtype of EDS will be analysed by next generation sequencing in order to identify the causal genetic defect. In a next step, the genome of a cohort of ...
The role of ROS signaling and redox state in the aging process of the nematode Caenorhabditis elegans Ghent University
The last decade many studies have shown that aging is correlated with but not caused by oxidative stress. Many of these studies have been performed in the model organism Caenorhabditis elegans. In dit research project we want to assess the role of redox signaling on the aging process of this nematode. This will be performed using genetically encoded sensors.
Selective catalytic conversion of cellulose fractions KU Leuven
Nowadays, there is a tremendous interest in greener alternatives to the petroleum-based production of fuels, chemicals and materials in classical refineries. The valorization of lignocellulosic biomass in so-called biorefineries could be an interesting alternative due to the renewable nature of biomass. Lignocellulose is an abundant biomaterial that can be found in cell walls of numerous plants like trees, grasses and energy crops and mainly ...