Uncovering liver macrophage subsets and the role of macrophage prolyl hydroxylases in the pathogenesis of non-alcoholic steatohepatitis and associated liver cancer Ghent University
Non-alcoholic fatty liver disease is an important cause of chronic liver disease in Western countries. The disease ranges from simple steatosis (lipid accumulation) to non-alcoholic steatohepatitis (NASH) (liver inflammation related to steatosis) which can result in liver cirrhosis and even in NASH-induced hepatocellular carcinoma (NASH-HCC). Macrophages (Mf) are innate immune cells with diverse functions related to their origin and local ...