Analysis and mining of signaling complexes using contemporary interactomics Ghent University
Protein interactions fulfil a critical role in a cell and their dysregulation contributes to human disease. We will apply an unique technology U+201CtoolboxU+201D comprising MAPPIT, PPI-iMixPro and VIROTRAP, combined with state-of-the-art bioinformatics approaches, to gain new insights into the (patho)fysiological roles of selected protein interactions. In addition, we will use nanobodies as intrabodies to disturb protein interactions in ...