Modulation of liver fibrosis by liposome-mediated selective targeting of hepatic stellate cells Vrije Universiteit Brussel
Chronic liver disease is a global health care problem. It develops as a consequence of chronic viral infections, drug or alcohol abuse, autoimmune disorders or as part of the metabolic syndrome. Independent of the causative factors, chronic liver injury leads to organ fibrosis and further develops to cirrhosis or hepatocellular carcinoma. Currently, no effective anti-fibrotic treatment is available and for nd-Â?stage liver disease patients liver ...