Researcher
Thierry Vandendriessche
- Keywords:Medicine, Applied biological sciences, biotechnology
- Disciplines:Hematology, Computational transcriptomics and epigenomics, Neurological and neuromuscular diseases, Cancer therapy , Cardiology
Affiliations
- Basic (bio-) Medical Sciences (Department)
Member
From1 Jan 2014 → Today - Division of Gene Therapy & Regenerative Medicine (Research group)
Responsible
From19 Apr 2011 → Today - Cell Biology and Histology (Department)
Member
From1 Oct 2010 → 31 Dec 2013 - Department of Bio-engineering Sciences (Department)
Member
From1 Oct 2003 → 30 Sep 2004, 1 Feb 2007 → 30 Sep 2010 - Immunology and Microbiology (Department)
Member
From1 Oct 2007 → 30 Sep 2010 - Department of General Biology (Research group)
Member
From1 Oct 1990 → 30 Sep 1994
Projects
1 - 10 of 13 results
- UPGRADE: Unlocking Precision Gene Therapy (OZR EU Bonus)From1 Jan 2019 → TodayFunding: BOF - Other initiatives
- UPGRADE: Unlocking Precision Gene TherapyFrom1 Jan 2019 → TodayFunding: H2020 - Health; demographic change and wellbeing
- GENEFIX: Development of muscle-targeted gene therapy for hemophilia B using longer-acting clotting factor IXFrom1 Jan 2016 → 31 Dec 2019Funding: FWO research project
- Advanced T-cell Therapy for Augmented Cancer Killing ("ATTACK"): next-generation T-cell immunotherapy directed against lymphoid malignanciesFrom1 Jan 2016 → 31 Dec 2019Funding: FWO research project
- Financing IOF-program GEAR: Hyperactieve Expressie-modulesFrom1 Apr 2014 → 31 Mar 2020Funding: IOF - Industrial Research Fund
- SRP (Groeiers): Next-generation gene therapy by computational vector design and immune stealth nanotechnologyFrom1 Mar 2014 → 28 Feb 2019Funding: BOF - Concerted Research Project from 1994
- miRNA modulation in cancer with the help of designer Transcription Activator-Like Effector Nucleases (TALENs): a new platform for oncological researchFrom1 Jan 2014 → 31 Dec 2017Funding: FWO research project
- Development of non-viral gene therapy for hemophilia with innovative hyperactive transposon technologyFrom1 Jan 2014 → 31 Dec 2017Funding: FWO research project
- IOF proof of Concept: Clinical translation of gene therapy for hemophilia, consolidation of a spin-off companyFrom1 Nov 2013 → 31 Oct 2015Funding: IOF - Industrial Research Fund
- Cardiovascular and muscle-specific "targeting" for gene therapy of neuromuscular disordersFrom1 Jan 2013 → 31 Dec 2016Funding: FWO research project
Publications
1 - 10 of 88 results
- Identification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants(2020)
Authors: Jonas Weinmann, Sabrina Weis, Josefine Sippel, Warut Tulalamba, Anca Remes, Jihad El Andari, Anne-Kathrin Herrmann, Quang H Pham, Christopher Borowski, Susanne Hille, et al.
- Towards a global multidisciplinary consensus framework on haemophilia gene therapy(2020)
Authors: Glenn F Pierce, K John Pasi, Donna Coffin, Radoslaw Kaczmarek, David Lillicrap, Johnny Mahlangu, Dawn Rottellini, Thomas Sannié, Alok Srivastava, Thierry VandenDriessche, et al.
Pages: 443-449Number of pages: 7 - Genetic and Epigenetic Modification of Rat Liver Progenitor Cells via HNF4α Transduction and 5’ Azacytidine Treatment: An Integrated miRNA and mRNA Expression Profile Analysis(2020)
Authors: Jennifer Bolleyn, Matthias Rombaut, N. Nair, Steven Branson, Anja Heymans, Anja Heymans, Marinee Chuah, Thierry VandenDriessche, Vera Rogiers, Joery De Kock, et al.
Pages: 62-80Number of pages: 18 - Distinct transduction of muscle tissue in mice after systemic delivery of AAVpo1 vectors(2020)
Authors: Warut Tulalamba, Jonas Weinmann, Hong Quang Pham, Jihad El Andari, Thierry VandenDriessche, Marinee Chuah, Dirk Grimm
Pages: 170-179Number of pages: 10 - Validation of miR-20a as a Tumor Suppressor Gene in Liver Carcinoma Using Hepatocyte-Specific Hyperactive piggyBac Transposons(2020)
Authors: Jaitip Tipanee, Mario Di Matteo, Warut Tulalamba, Ermira Samara-Kuko, Jiri Keirsse, Jo A Van Ginderachter, Marinee K Chuah, Thierry VandenDriessche
Pages: 1309-1329Number of pages: 21 - Hemophilia gene therapy knowledge and perceptions(2020)
Authors: Flora Peyvandi, David Lillicrap, Johnny Mahlangu, Claire McLintock, K John Pasi, Steven W Pipe, Wendy Scales, Alok Srivastava, Thierry VandenDriessche
Pages: 644-651Number of pages: 8 - Next-generation muscle-directed gene therapy by in silico vector design(2019)
Authors: Shilpita Sarcar, Warut Tulalamba, Melvin Rincon Acelas, Jaitip Tipanee, Hong Quang Pham, Hanneke Evens, Dimitri Boon, Marleen Keyaerts, Mariana Loperfido, Pieter In 'T Veld, et al.
Pages: 492Number of pages: 18 - Muscle Gene Therapy(2019)
Authors: Thierry Vandendriessche, Dimitri Boon, Marinee Chuah
Pages: 81-97Number of pages: 17 - Efficient CRISPR/Cas9-mediated editing of trinucleotide repeat expansion in myotonic dystrophy patient-derived iPS and myogenic cells(2018)
Authors: Sumitava Dastidar, Simon Ardui, Kshitiz Singh, Debanjana Majumdar, Nisha Nair Dastidar, Yanfang Fu, Deepak Reyon, Ermira Samara, Mattia FM Gerbil, Arnaud F. Klein, et al.
Pages: 8275-8298Number of pages: 24 - A Calsequestrin Cis-Regulatory Motif Coupled to a Cardiac Troponin T Promoter Improves Cardiac Adeno-Associated Virus Serotype 9 Transduction Specificity(2018)
Authors: Kyle Chamberlain, Jalish Mahmud Riyad, Tyrone Garnett, Erik Kohlbrenner, Ananda Mookerjee, Firas Elmastour, Ludovic Benard, Jiqiu Chen, Thierry VandenDriessche, Marinee K Chuah, et al.
Pages: 927-937Number of pages: 11