Projects
Link between residual beta cell function and glycemic variability in (pre)type 1 diabetes Vrije Universiteit Brussel
Relation between residual beta cell function and glycemic variability in (pre)type 1 diabetes. University of Antwerp
Relation between residual beta cell function and glycemic variability in (pre) type 1 diabetes Ghent University
Type 1 diabetes develops when 60 to 90% of insulin-producing beta cellsahve been destroyed. This cell loss leads to greater variability of
blood glucose levels both before and after diagnosis. This variability is predictive of progression to clinical onset of diabetes in risk groups and of
frequenc of hypoglycemic events in patients. Novel beta cell therapy trials aim to prevent or cure diabetes by trying to preserve or restore ...
The association between new parameters of glycaemic control and arterial stiffness in type 1 diabetes, and its modulation by high-intensity interval exercise. Ghent University
BACKGROUND 1. New parameters of glycaemic control by use of continuous glucose monitoring (CGM; such as time in range, glycaemic variability) are of increasing interest in type 1 diabetes (T1DM) clinical practice. Poor glycaemic control negatively affects arterial stiffness, a valuable predictor for cardiovascular disease. However, reliable data using the state-of-the-art methodology (i.e. CGM) are missing. 2. Easy implementable strategies to ...
INTERPLAY WITHIN THE DAY: optimizing intra-day glucose control by intervening on the day-to-day 24-hour movement behavior patterns in adults with type 1 diabetes mellitus. Ghent University
Only 24.9% of the Belgian adults (25-50 years) with type 1 diabetes mellitus (T1DM) achieve the glycemic target. This can be explained by the challenging day-to-day diabetes management which places a substantial burden on this population. However, a tight glucose control is fundamental in order to prevent the development of acute and chronic complications. Despite the added value of continue glucose monitors to glucose control, optimizing ...
INTERPLAY WITHIN THE DAY: optimizing intra-day glucose control by intervening on the day-to-day 24-hour movement behavior patterns in adults with type 1 diabetes mellitus. University of Antwerp
MRNA therapy for experimental beta(-like) cell transplantation Vrije Universiteit Brussel
Predicting impending beta cell loss and dysglycemia in asymptomatic type 1 diabetes - Validation of minimally invasive markers against the hyperglycemic clamp test. Vrije Universiteit Brussel
the gold standard hyperglycemic clamp test (HCT) in asymptomatic
type 1 diabetes (T1D) in relation to known determinants of disease
progression. This may help to unravel the heterogeneous nature of
pre-T1D. The majority of beta cell loss is hypothesized to occur within
2 years prior to diagnosis. Simultaneously, promising minimally
...