Combining in silico and in vivo approaches to unravel the accessory function of liver-resident macrophages Ghent University
Macrophages (MFs) were originally identified by the Nobel laureate Ilya Metchnikoff as cells specialized in the killing of micro-organisms. However, genetic profiling of MFs from various tissues has demonstrated the astonishing diversity of MFs, suggesting that each MF is profoundly adapted to its tissue of residence and performs unique local functions. However, what these unique functions might be is only poorly understood. We hypothesize ...