Publications
Buruli ulcer; review of a reemerging mycobacterial disease Institute of Tropical Medicine
Traditional treatment of Buruli ulcer in Benin Institute of Tropical Medicine
Contribution to the improvement of the control of Buruli ulcer in the territory of Songololo : impact of the decentralization and integration of control activities in basic health services Institute of Tropical Medicine
Improving clinical and epidemiological predictors of Buruli ulcer Institute of Tropical Medicine
BACKGROUND: Buruli ulcer (BU) is a chronic necrotizing infectious skin disease caused by Mycobacterium ulcerans. The treatment with BU-specific antibiotics is initiated after clinical suspicion based on the WHO clinical and epidemiological criteria. This study aimed to estimate the predictive values of these criteria and how they could be improved.
METHODOLOGY/PRINCIPAL FINDINGS: A total of 224 consecutive patients presenting with ...
Mycobacterium ulcerans population genomics to inform on the spread of Buruli Ulcer across Central Africa University of Antwerp
Comparative genomics showsmigration and expansion has preceded the rise of Buruli ulcer in south-eastern Australia Institute of Tropical Medicine
Since 2012, cases of the neglected tropical disease Buruli ulcer, caused by infection withMycobacterium ulcerans,have increased 100-fold since 2000 around Melbourne, (population 4.4 million) the capital of Victoria in temperate south-eastern Australia. The reasons for this increase are unclear. Here, we have used whole genome sequence comparisons of 178M. ulceransisolates obtained primarily from human clinical specimens, spanning 70 years, to ...
Amoebae as potential environmental hosts for **Mycobacterium ulcerans** and other mycobacteria, but doubtful actors in Buruli ulcer epidemiology University of Antwerp
Buruli ulcer in traveler from Suriname, South America, to the Netherlands Institute of Tropical Medicine
We report Buruli ulcer in a man in the Netherlands. Phenotyping of samples indicate the Buruli pathogen was acquired in Suriname and activated by trauma on return to the Netherlands. Awareness of this disease by clinicians in non-Buruli ulcer-endemic areas is critical for identification.
Whole genome comparisons suggest random distribution of Mycobacterium ulcerans genotypes in a Buruli ulcer endemic region of Ghana Institute of Tropical Medicine University of Antwerp
Efforts to control the spread of Buruli ulcer--an emerging ulcerative skin infection caused by Mycobacterium ulcerans--have been hampered by our poor understanding of reservoirs and transmission. To help address this issue, we compared whole genomes from 18 clinical M. ulcerans isolates from a 30 km2 region within the Asante Akim North District, Ashanti region, Ghana, with 15 other M. ulcerans isolates from elsewhere in Ghana and the ...