The pulmonary and cardiovascular effects of chronic exposure to nanomaterials, emphasis on inflammation and atherosclerosis. KU Leuven
In general, the conceptual objective of the study is that pulmonary exposure to engineered nanoparticles (NPs) may induce systemic effects which are relevant to atherogenesis or the progression of atherosclerosis. The toxicological testing of NPs will include physico-chemical characterization of nanomaterials used, in vitro assays, and in vivo studies. All exposures will be performed using low concentrations of NPs and, when applicable, chronic ...