Publications
Clinical and diagnostic aspects of tenosynovitis of the digital flexor tendon sheath Ghent University
Inbreeding in the Belgian equine warmblood population : current degree and evolution Ghent University
A tremendous evolution has taken place in the field of equine reproduction during the past decade. Advanced reproduction techniques, such as ovum pick up combined with intracytoplasmic sperm injection and embryo transfer, have become more and more routine procedures in warmblood breeding. These techniques allow ‘popular’ mares to produce multiple foals per year via surrogate mares. The latter evolution and the impression that only a limited ...
Successful genotype imputation from medium to high density in Belgian Warmblood horses Ghent University
Genotype imputation is a method that infers unobserved genotypes in a sample of individuals using a reference population. Genotype imputation permits increasing the density of available genotypes within a population and combining genotypes from different density SNP arrays and can therefore improve the power of genomic studies. Here, we investigate the feasibility of genotype imputation from medium to high density SNP arrays in Belgian Warmblood ...
A survey on Flemish veterinary practitioners’ experience with stem cell therapy to treat equine tendon injuries Ghent University
Horses in all equestrian disciplines are suffering from tendon injuries followed by several months of rehabilitation. Additionally, the scar tissue formed after injury is of inferior quality, resulting in high re-injury rates. Conventional treatments include rest, controlled exercise and anti-inflammatory drugs administration. In order to improve tissue regeneration and prevent reinjury, biological treatments, such as mesenchymal stem cells ...
Profiling the aerobic window of horses in response to training by means of a modified lactate minimum speed test : flatten the curve Ghent University
Cellular and humoral immunogenicity investigation of single and repeated allogeneic tenogenic primed mesenchymal stem cell treatments in horses suffering from tendon injuries Ghent University
The use of mesenchymal stem cells (MSCs) for the treatment of equine tendon disease is widely investigated because of their regenerative and immunomodulatory potential. However, questions have been raised concerning the immunogenic properties of allogeneic MSCs. Therefore, two studies were conducted to assess the safety of equine allogeneic peripheral blood-derived tenogenic primed MSCs (tpMSCs). The objective was to evaluate if a single and ...
Assessing the functional properties of tenogenic primed mesenchymal stem cells in ex vivo equine tendon and ligament explants : a preliminary study Ghent University
Injuries to equine tendons and ligaments are career-compromising, causing reduced performance and premature retirement. Promising treatment alternatives have been investigated in the field of mesenchymal stem cells (MSCs). In this study, the tissue adherence and protein expression of tenogenic primed mesenchymal stem cells (tpMSCs) after administration to ex vivo tendon and ligament explants is investigated. First, collagen type I (COL I) and ...