Exploring the purinergic P2Y2 receptor as a novel target for effective treatment of vascular calcification. University of Antwerp
Vascular calcification is a major clinical problem, particularly in elderly and patients suffering from chronic kidney disease and diabetes, and has a significant impact on morbidity and mortality by provoking severe cardiovascular events. Current therapies focus on controlling some of the multiple risk factors and therefore lack efficiency. As such, effective therapies to prevent and stop the rapid progression of vascular calcification in both ...