Researcher
Yvette Michotte
- Research Expertise:
- Design and statistical analysis of clinical studies; Use of mathematical models for the evaluation of medical data;
- Neurochemistry. Pharmacokinetics. Drug analysis. Biostatistics. Pharmaceutical registration dossier and expert reports.
- Keywords:Pharmacy and pharmacology, Medicine, General and logistic services, Earth sciences and geography
- Disciplines:Biomarker discovery, Intensive care anaesthesiology, Stem cell biology, General and logistic services
- Users of research expertise:
- Design and statistical analysis of clinical studies; Use of mathematical models for the evaluation of medical data;
- Neurochemistry. Pharmacokinetics. Drug analysis. Biostatistics. Pharmaceutical registration dossier and expert reports.
Affiliations
- Rectorate (Administrative office)
Member
From1 Oct 2023 → Today - Education (Administrative office)
Member
From1 Oct 2022 → 30 Sep 2023 - Education (Administrative office)
Member
From1 Oct 2022 → 20 Oct 2022 - Education (Administrative office)
Member
From1 May 2019 → 30 Sep 2022 - Vriendenkring VUB (Office)
Member
From8 Apr 2019 → Today - RC Academic Unit (Office)
Member
From15 Oct 2016 → 14 Jul 2018 - Pharmaceutical and Pharmacological Sciences (Department)
Member
From1 Jan 2014 → 30 Sep 2016 - Experimental Pharmacology (Research group)
Member
From19 Nov 2003 → 6 Apr 2021 - Pharmaceutical Chemistry, Drug Analysis and Drug Information (Department)
Member
From1 Oct 1991 → 31 Dec 2013 - Pharmacology (Department)
Member
From1 Oct 1982 → 30 Sep 1991 - Pharmacology (Department)
Member
From1 Oct 1972 → 30 Sep 1986
Projects
1 - 6 of 6
- SRP (Zwaartepunt): Pathways of astrocyte-neuron: interactions and disease modifying therapies in neurological disorders. (Herwerking B- geklasseerde SRP)From1 Oct 2013 → 30 Sep 2017Funding: BOF - Concerted Research Project from 1994
- In search for anticonvulsive and antiepileptogenic neuropeptides as a strategy for innovative future antiepileptic drug developmentFrom1 Jan 2010 → 31 Dec 2013Funding: FWO research project (including WEAVE projects)
- Neuro-TARGET : integrated platform for target identification, validation and drug discovery with applications for neurodegenerative diseases.From1 Jan 2009 → 31 Dec 2012Funding: SBO (Strategic basic research)
- Study of the central neurobiochemical alterations elicited by modulation of the AT4 receptor/insulin-regulated aminopeptidase (IRAP), therapeutic pprospects for cognitive dysfunction and limbic epilepsyFrom1 Jan 2008 → 31 Dec 2011Funding: Private funding of national origin - undefined
- Pharmacokinetic and pharmacodynamic markers and correlation studies for the pharmacotherapy optimization of antiepileptic drugsFrom1 Jan 2008 → 31 Dec 2008Funding: FWO research grant KAN
- The role of insulin-like growth factor-I in protection and regeneration after transient focal brain ischemiaFrom1 Jan 2008 → 31 Dec 2011Funding: FWO research project (including WEAVE projects)
Publications
1 - 10 of 81
- Quantification of piritramide in human colostrum(2017)
Authors: Ann Van Eeckhaut, J Van Schoors, Yannick Van Wanseele, Jan Poelaert, Yvette Michotte, Patsy Simonne V Vanfleteren
Pages: 306-310 - Reassessment of the antioxidative mixture for the challenging electrochemical determination of dopamine, noradrenaline and serotonin in microdialysis samples(2015)
Authors: J Van Schoors, Charlotte Lens, Katrien Maes, Yvette Michotte, Ilse Smolders, Ann Van Eeckhaut
Pages: 63-71 - Absence of system xc- in mice decreases anxiety and depressive-like behavior without affecting sensorimotor function or spatial vision(2015)
Authors: Eduard Bentea, Thomas Demuyser, Joeri Van Liefferinge, Giulia Albertini, Lauren Deneyer, Julie Nys, Ellen Merckx, Yvette Michotte, Hideyo Sato, Lutgarde Arckens, et al.
Pages: 49-58 - An ultrasensitive nano UHPLC-ESI-MS/MS method for the quantification of three neuromedin-like peptides in microdialysates(2015)
Authors: Katrien Maes, Guillaume Béchade, J Van Schoors, Yannick Van Wanseele, Joeri Van Liefferinge, Yvette Michotte, Stephanie N. Harden, Erin E Chambers, Jan Claereboudt, Ilse Smolders, et al.
Pages: 605-619 - Longitudinal follow-up and characterization of a robust rat model for Parkinson's disease based on overexpression of alpha-synuclein with adeno-associated viral vectors.(2015)
Authors: , Jaan Toelen, Cindy Casteels, Francesca Macchi, Anne-Sophie Van Rompuy, Sophie Sarre, Nicolas Casadei, Silke Nuber, Uwe Himmelreich, Maria Isabel Osorio Garcia, et al.
Pages: 1543-1558 - Nigral proteasome inhibition in mice leads to motor and non-motor deficits and increased expression of Ser129 phosphorylated α-synuclein(2015)
Authors: Eduard Bentea, , Joeri Van Liefferinge, Anissa El Arfani, Giulia Albertini, Thomas Demuyser, Ellen Merckx, Yvette Michotte, Ilse Smolders, Veerle Baekelandt, et al.
- Strategies to reduce aspecific adsorption of peptides and proteins in liquid chromatography-mass spectrometry based bioanalyses: An overview(2014)
Authors: Katrien Maes, Ilse Smolders, Yvette Michotte, Ann Van Eeckhaut
Pages: 1-13 - Improved sensitivity of the nano ultra-high performance liquid chromatography-tandem mass spectrometric analysis of low-concentrated neuropeptides by reducing aspecific adsorption and optimizing the injection solvent(2014)
Authors: Katrien Maes, Joeri Van Liefferinge, Johan Viaene, J Van Schoors, Yannick Van Wanseele, Guillaume Béchade, E. Chambers, Hugo Morren, Yvette Michotte, Y Vander Heyden, et al.
Pages: 217-228 - Cortistatin-14 Mediates its Anticonvulsant Effects Via sst2 and sst3 but Not Ghrelin Receptors(2014)
Authors: Najat Aourz, Jeanelle Portelli, Jessica Coppens, Dimitri De Bundel, G. Di Giovanni, Ann Van Eeckhaut, Yvette Michotte, Ilse Smolders
Pages: 662-670 - NMDA receptor antagonism potentiates the L-DOPA-induced extracellular dopamine release in the subthalamic nucleus of hemi-parkinson rats(2014)
Authors: Anissa El Arfani, Eduard Bentea, Najat Aourz, Ben Ampe, P. De Deurwaerdere, Ann Van Eeckhaut, Ann Massie, Sophie Sarre, Ilse Smolders, Yvette Michotte
Pages: 198-205