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Researcher
Wim De Borggraeve
- Disciplines:Medicinal and biomolecular chemistry not elsewhere classified, Bio-organic chemistry, Organic chemical synthesis, Organic green chemistry
Affiliations
- Sustainable Chemistry for Metals and Molecules (Division)
Member
From1 Oct 2004 → Today
Projects
1 - 10 of 40
- Synthesis of thiazyl fluorides and derived compoundsFrom30 Nov 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Thiazyl fluorides: introducing S≡N triple bonds into SuFEx warheads for protein profilingFrom1 Nov 2023 → TodayFunding: FWO senior postdoctoral fellowship
- Towards an efficient treatment of drug-resistant epilepsy: unravelling the antiseizure mode of action of lead compound 10.1From27 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Targeting the androgen receptor dimerisation via computer-aided drug design and high throughput synthesis for prostate cancer therapy.From1 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Building molecules using a Unified Computational and Organic Reaction Network (UniCORN).From1 Oct 2022 → 30 Sep 2023Funding: BOF - postdoctoral mandates
- Discovery of novel bioactive natural compounds from symbiotic microorganisms (DiNoBiNaC)From1 Oct 2021 → 30 Sep 2023Funding: BOF - projects
- PhD position - Organic synthesis of fluorinated compoundsFrom27 May 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- PhD position - Organic synthesis of fluorinated compoundsFrom10 May 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Enabling SF5 introduction: Paving the way toward unexplored bioisosteres and novel PET radiotracersFrom1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Development of new chemical tools to investigate the role of L-type calcium channels in diseases.From6 Oct 2020 → TodayFunding: FWO Strategic Basic Research Grant
Publications
151 - 160 of 177
- Synthesis and application of reactive BODIPY dyes.(2010)
Authors: Volker Leen, Wim Dehaen, Wim De Borggraeve
- Influence of Reducing Carbohydrates on (6S)-5-Methyltetrahydrofolic Acid Degradation during Thermal Treatments(2010)
Authors: Lien Lemmens, Wim De Borggraeve, Marc Hendrickx, Ann Van Loey
Pages: 6190 - 6199 - Generalized solvent scales as a tool for investigating solvent dependence of spectroscopic and kinetic parameters. Application to fluorescent BODIPY dyes(2010)
Authors: Gosia Kluba, Lesley Pandey, Wim De Borggraeve, Mark Van der Auweraer, Noël Boens
Pages: 996 - 1008 - Direct functionalization of BODIPY dyes by oxidative nucleophilic hydrogen substitution at the 3-or 3,5-positions(2010)
Authors: Wim De Borggraeve, Noël Boens, Wim Dehaen
Pages: 4908 - 4910 - Synthesis and Substitution of 8-(4,6-Dichloropyrimidin-5-yl)-BODIPY(2009)
Authors: Volker Leen, Wim De Borggraeve, Noël Boens, Wim Dehaen
Pages: 5920 - 5926 - Synthesis and Biological Evaluation of Bridged Analogues of the Platelet Aggregation Inhibitor Trifenagrel(2009)
Authors: Wim De Borggraeve, Georges Hoornaert, Koen Robeyns, Luc Van Meervelt
Pages: 478 - 486 - Flavonoids from Senecio viscosus(2009)
Authors: Rani Jose, Wim De Borggraeve, Wim Dehaen
Pages: 731 - 732 - Mechanism and Related Kinetics of 5-Methyltetrahydrofolic Acid Degradation during Combined High Hydrostatic Pressure-Thermal Treatments(2009)
Authors: Inneke Oey, Wim De Borggraeve, Marc Hendrickx, Ann Van Loey
Pages: 6803 - 6814 - Synthesis and modifications of a small library of 1,4-benzodiazepin-3-ones toward potential inhibitors of the collagen-von Willebrand Factor interaction(2009)
Authors: Tiny Deschrijver, Peter Verwilst, Katleen Broos, Hans Deckmyn, Wim Dehaen, Wim De Borggraeve
Pages: 4521 - 4529 - Synthesis of 5,5'-Dialkyl-6,6'-dichloro-2, 2'-bipyridines(2009)
Authors: Wim De Borggraeve, Wim Dehaen
Pages: 927 - 939
Patents
1 - 3 of 3
- Treatment of pharmacoresistant epilepsy (Inventor)
- DAN SHEN EXTRACTS AND COMPOUNDS (Inventor)
- ANTI-FUNGAL COMPOSITIONS (Inventor)